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Albert P Li

Showing results (31-40 of 77) with videos related to

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Drug Metabolism Letters|June 10, 2014
Application of a higher throughput approach to derive apparent Michaelis-Menten constants of isoform-selective p450-mediated biotransformation reactions in human hepatocytesAlbert P Li, Kari E Schlicht
Chemico-Biological Interactions|November 4, 2004
A novel in vitro system, the integrated discrete multiple organ cell culture (IdMOC) system, for the evaluation of human drug toxicity: comparative cytotoxicity of tamoxifen towards normal human cells from five major organs and MCF-7 adenocarcinoma breast cancer cellsAlbert P Li, Chris Bode, Yumiko Sakai
Chemico-Biological Interactions|January 1, 2016
In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuriesDoshi Utkarsh, Carol Loretz, Albert P Li
Chemico-Biological Interactions|May 30, 2012
Definition of metabolism-dependent xenobiotic toxicity with co-cultures of human hepatocytes and mouse 3T3 fibroblasts in the novel integrated discrete multiple organ co-culture (IdMOC) experimental system: results with model toxicants aflatoxin B1, cyclophosphamide and tamoxifenAlbert P Li, Aarti Uzgare, Yumiko S LaForge
Current Drug Metabolism|April 6, 2012
Effects of culture duration on gene expression of P450 isoforms, uptake and efflux transporters in primary hepatocytes cultured in the absence and presence of interleukin-6: implications for experimental design for the evaluation of downregulatory effects of biotherapeuticsQian Yang, Utkarsh Doshi, Nicole Li, et al.
Drug Metabolism Letters|August 21, 2018
A Novel In vitro Experimental System for the Evaluation of Enteric Drug Metabolism: Cofactor-Supplemented Permeabilized Cryopreserved Human Enterocytes (MetMax™ Cryopreserved Human Enterocytes)Albert P Li, Kirsten Amaral, Ming-Chih D Ho
Drug Metabolism Letters|August 19, 2015
A Novel Plated Hepatocyte Relay Assay (PHRA) for In Vitro Evaluation of Hepatic Metabolic Clearance of Slowly Metabolized CompoundsChi-Chi Peng, Utkarsh Doshi, Chandra Prakash, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 25, 2018
A Novel In Vitro Experimental System for the Evaluation of Drug Metabolism: Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Cryopreserved Human Hepatocytes)Albert P Li, Ming-Chih David Ho, Kirsten Amaral, et al.
Biochemical Pharmacology|December 28, 2020
Prolonged cultured human hepatocytes as an in vitro experimental system for the evaluation of potency and duration of activity of RNA therapeutics: Demonstration of prolonged duration of gene silencing effects of a GalNAc-conjugated human hypoxanthine phosphoribosyl transferase (HPRT1) siRNAQian Yang, Sara C Humphreys, Julie M Lade, et al.
Regulatory Toxicology and Pharmacology : RTP|August 20, 2010
Cytotoxicity of eight cigarette smoke condensates in three test systems: comparisons between assays and condensatesPatricia A Richter, Albert P Li, Gregory Polzin, et al.
Pageof 8

Showing results (31-40 of 77) with videos related to

Sort By:
Pageof 8
Drug Metabolism Letters|June 10, 2014
Application of a higher throughput approach to derive apparent Michaelis-Menten constants of isoform-selective p450-mediated biotransformation reactions in human hepatocytesAlbert P Li, Kari E Schlicht
Chemico-Biological Interactions|November 4, 2004
A novel in vitro system, the integrated discrete multiple organ cell culture (IdMOC) system, for the evaluation of human drug toxicity: comparative cytotoxicity of tamoxifen towards normal human cells from five major organs and MCF-7 adenocarcinoma breast cancer cellsAlbert P Li, Chris Bode, Yumiko Sakai
Chemico-Biological Interactions|January 1, 2016
In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuriesDoshi Utkarsh, Carol Loretz, Albert P Li
Chemico-Biological Interactions|May 30, 2012
Definition of metabolism-dependent xenobiotic toxicity with co-cultures of human hepatocytes and mouse 3T3 fibroblasts in the novel integrated discrete multiple organ co-culture (IdMOC) experimental system: results with model toxicants aflatoxin B1, cyclophosphamide and tamoxifenAlbert P Li, Aarti Uzgare, Yumiko S LaForge
Current Drug Metabolism|April 6, 2012
Effects of culture duration on gene expression of P450 isoforms, uptake and efflux transporters in primary hepatocytes cultured in the absence and presence of interleukin-6: implications for experimental design for the evaluation of downregulatory effects of biotherapeuticsQian Yang, Utkarsh Doshi, Nicole Li, et al.
Drug Metabolism Letters|August 21, 2018
A Novel In vitro Experimental System for the Evaluation of Enteric Drug Metabolism: Cofactor-Supplemented Permeabilized Cryopreserved Human Enterocytes (MetMax™ Cryopreserved Human Enterocytes)Albert P Li, Kirsten Amaral, Ming-Chih D Ho
Drug Metabolism Letters|August 19, 2015
A Novel Plated Hepatocyte Relay Assay (PHRA) for In Vitro Evaluation of Hepatic Metabolic Clearance of Slowly Metabolized CompoundsChi-Chi Peng, Utkarsh Doshi, Chandra Prakash, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 25, 2018
A Novel In Vitro Experimental System for the Evaluation of Drug Metabolism: Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Cryopreserved Human Hepatocytes)Albert P Li, Ming-Chih David Ho, Kirsten Amaral, et al.
Biochemical Pharmacology|December 28, 2020
Prolonged cultured human hepatocytes as an in vitro experimental system for the evaluation of potency and duration of activity of RNA therapeutics: Demonstration of prolonged duration of gene silencing effects of a GalNAc-conjugated human hypoxanthine phosphoribosyl transferase (HPRT1) siRNAQian Yang, Sara C Humphreys, Julie M Lade, et al.
Regulatory Toxicology and Pharmacology : RTP|August 20, 2010
Cytotoxicity of eight cigarette smoke condensates in three test systems: comparisons between assays and condensatesPatricia A Richter, Albert P Li, Gregory Polzin, et al.
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