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Chemico-Biological Interactions
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November 20, 2015
Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles
Jie Zhang, Utkarsh Doshi, Ayako Suzuki, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
August 4, 2019
Development and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes)
Veera Raghava Choudary Palacharla, Prathyusha Chunduru, Devender Reddy Ajjala, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
February 2, 2018
Prediction of the Pharmacokinetics of Pravastatin as an OATP Substrate Using Plateable Human Hepatocytes With Human Plasma Data and PBPK Modeling
Jialin Mao, Utkarsh Doshi, Matthew Wright, et al.
Drug Metabolism Letters
|
March 18, 2014
Culture duration-, donor-, and medium-dependent changes in OATP1B3-mediated telmisartan uptake in human hepatocytes
Qing Zhu, Haiyan Xia, Cindy Q Xia, et al.
The Journal of Pharmacy and Pharmacology
|
November 8, 2003
Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin
Leah M Hesse, Yumiko Sakai, Daesety Vishnuvardhan, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 15, 2018
Cryopreserved Human Intestinal Mucosal Epithelium: A Novel In Vitro Experimental System for the Evaluation of Enteric Drug Metabolism, Cytochrome P450 Induction, and Enterotoxicity
Albert P Li, Novera Alam, Kirsten Amaral, et al.
Chemico-Biological Interactions
|
October 26, 2002
Correlation between troglitazone cytotoxicity and drug metabolic enzyme activities in cryopreserved human hepatocytes
Nicola J Hewitt, Scott Lloyd, Mike Hayden, et al.
Chemico-Biological Interactions
|
October 26, 2002
Identification of glutathione conjugates of troglitazone in human hepatocytes
Saileta Prabhu, Andrew Fackett, Scott Lloyd, et al.
Biochemical Pharmacology
|
July 21, 2018
Strategies and limitations associated with in vitro characterization of vitamin D receptor activators
Paola Bukuroshi, Hiroshi Saitoh, Lilia Magomedova, et al.
Chemico-Biological Interactions
|
October 26, 2002
Differential in vitro hepatotoxicity of troglitazone and rosiglitazone among cryopreserved human hepatocytes from 37 donors
Scott Lloyd, Michael J Hayden, Yumiko Sakai, et al.
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Search research articles
Search
Showing results (51-60 of 77) with videos related to
Sort By:
Page
of 8
Chemico-Biological Interactions
|
November 20, 2015
Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles
Jie Zhang, Utkarsh Doshi, Ayako Suzuki, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
August 4, 2019
Development and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes)
Veera Raghava Choudary Palacharla, Prathyusha Chunduru, Devender Reddy Ajjala, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
February 2, 2018
Prediction of the Pharmacokinetics of Pravastatin as an OATP Substrate Using Plateable Human Hepatocytes With Human Plasma Data and PBPK Modeling
Jialin Mao, Utkarsh Doshi, Matthew Wright, et al.
Drug Metabolism Letters
|
March 18, 2014
Culture duration-, donor-, and medium-dependent changes in OATP1B3-mediated telmisartan uptake in human hepatocytes
Qing Zhu, Haiyan Xia, Cindy Q Xia, et al.
The Journal of Pharmacy and Pharmacology
|
November 8, 2003
Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin
Leah M Hesse, Yumiko Sakai, Daesety Vishnuvardhan, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 15, 2018
Cryopreserved Human Intestinal Mucosal Epithelium: A Novel In Vitro Experimental System for the Evaluation of Enteric Drug Metabolism, Cytochrome P450 Induction, and Enterotoxicity
Albert P Li, Novera Alam, Kirsten Amaral, et al.
Chemico-Biological Interactions
|
October 26, 2002
Correlation between troglitazone cytotoxicity and drug metabolic enzyme activities in cryopreserved human hepatocytes
Nicola J Hewitt, Scott Lloyd, Mike Hayden, et al.
Chemico-Biological Interactions
|
October 26, 2002
Identification of glutathione conjugates of troglitazone in human hepatocytes
Saileta Prabhu, Andrew Fackett, Scott Lloyd, et al.
Biochemical Pharmacology
|
July 21, 2018
Strategies and limitations associated with in vitro characterization of vitamin D receptor activators
Paola Bukuroshi, Hiroshi Saitoh, Lilia Magomedova, et al.
Chemico-Biological Interactions
|
October 26, 2002
Differential in vitro hepatotoxicity of troglitazone and rosiglitazone among cryopreserved human hepatocytes from 37 donors
Scott Lloyd, Michael J Hayden, Yumiko Sakai, et al.
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