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Emerging Topics in Life Sciences
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February 2, 2021
Neutron macromolecular crystallography
Matthew P Blakeley, Alberto D Podjarny
Proteins
|
May 18, 2004
Virtual screening for inhibitors of human aldose reductase
Oliver Kraemer, Isabelle Hazemann, Alberto D Podjarny, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 3, 2009
Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications
Michael C Van Zandt, Brian Doan, Diane R Sawicki, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
November 3, 2010
Neutron macromolecular crystallography with LADI-III
Matthew P Blakeley, Susana C M Teixeira, Isabelle Petit-Haertlein, et al.
ACS Chemical Biology
|
July 1, 2016
IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors
Alexandra Cousido-Siah, Francesc X Ruiz, Jindřich Fanfrlík, et al.
ACS Chemical Biology
|
April 29, 2015
The Effect of Halogen-to-Hydrogen Bond Substitution on Human Aldose Reductase Inhibition
Jindřich Fanfrlík, Francesc X Ruiz, Aneta Kadlčíková, et al.
Journal of Medicinal Chemistry
|
August 14, 2019
Discovery of <i>N</i>-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II
Michael C Van Zandt, G Erik Jagdmann, Darren L Whitehouse, et al.
Bioorganic & Medicinal Chemistry
|
October 7, 2004
Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications
Michael C Van Zandt, Evelyn O Sibley, Erin E McCann, et al.
Journal of Medicinal Chemistry
|
April 29, 2005
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications
Michael C Van Zandt, Michael L Jones, David E Gunn, et al.
Journal of Medicinal Chemistry
|
March 12, 2013
Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury
Michael C Van Zandt, Darren L Whitehouse, Adam Golebiowski, et al.
Page
of 1
Search research articles
Search
Showing results (1-10 of 10) with videos related to
Sort By:
Page
of 1
Emerging Topics in Life Sciences
|
February 2, 2021
Neutron macromolecular crystallography
Matthew P Blakeley, Alberto D Podjarny
Proteins
|
May 18, 2004
Virtual screening for inhibitors of human aldose reductase
Oliver Kraemer, Isabelle Hazemann, Alberto D Podjarny, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 3, 2009
Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications
Michael C Van Zandt, Brian Doan, Diane R Sawicki, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
November 3, 2010
Neutron macromolecular crystallography with LADI-III
Matthew P Blakeley, Susana C M Teixeira, Isabelle Petit-Haertlein, et al.
ACS Chemical Biology
|
July 1, 2016
IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors
Alexandra Cousido-Siah, Francesc X Ruiz, Jindřich Fanfrlík, et al.
ACS Chemical Biology
|
April 29, 2015
The Effect of Halogen-to-Hydrogen Bond Substitution on Human Aldose Reductase Inhibition
Jindřich Fanfrlík, Francesc X Ruiz, Aneta Kadlčíková, et al.
Journal of Medicinal Chemistry
|
August 14, 2019
Discovery of <i>N</i>-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II
Michael C Van Zandt, G Erik Jagdmann, Darren L Whitehouse, et al.
Bioorganic & Medicinal Chemistry
|
October 7, 2004
Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications
Michael C Van Zandt, Evelyn O Sibley, Erin E McCann, et al.
Journal of Medicinal Chemistry
|
April 29, 2005
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications
Michael C Van Zandt, Michael L Jones, David E Gunn, et al.
Journal of Medicinal Chemistry
|
March 12, 2013
Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury
Michael C Van Zandt, Darren L Whitehouse, Adam Golebiowski, et al.
Page
of 1