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Proceedings of the National Academy of Sciences of the United States of America|February 21, 2002
An NMR approach to structural proteomicsAdelinda Yee, Xiaoqing Chang, Antonio Pineda-Lucena, et al.Journal of Medicinal Chemistry|August 14, 2020
Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune DiseasesBrian S Gerstenberger, Catherine Ambler, Eric P Arnold, et al.Bioorganic & Medicinal Chemistry Letters|July 28, 2009
Optimization of the aminopyridopyrazinones class of PDE5 inhibitors: discovery of 3-[(trans-4-hydroxycyclohexyl)amino]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-oneRobert O Hughes, John K Walker, D Joseph Rogier, et al.Journal of Medicinal Chemistry|August 14, 2020
Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine GliomaDavid Smil, Jong Fu Wong, Eleanor P Williams, et al.RSC Medicinal Chemistry|March 22, 2024
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complexAliakbar Khalili Yazdi, Sumera Perveen, Cheng Dong, et al.ACS Chemical Biology|August 30, 2017
Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast DifferentiationJulia C Meier, Cynthia Tallant, Oleg Fedorov, et al.Journal of Medicinal Chemistry|April 27, 2016
Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment HitBrian S Gerstenberger, John D Trzupek, Cynthia Tallant, et al.RSC Medicinal Chemistry|February 25, 2022
Target 2035 - update on the quest for a probe for every proteinSusanne Müller, Suzanne Ackloo, Arij Al Chawaf, et al.Bioorganic & Medicinal Chemistry Letters|June 23, 2009
Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring systemRobert O Hughes, John K Walker, Jerry W Cubbage, et al.Nature Protocols|December 17, 2024
A consensus platform for antibody characterizationRiham Ayoubi, Joel Ryan, Sara Gonzalez Bolivar, et al.Pageof 15