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Human Reproduction (Oxford, England)|May 29, 2026
ABHD2 activity is not required for the non-genomic action of progesterone on human spermMadison Edwards, Alexandra Amaral, Eve M Carter, et al.Journal of Medicinal Chemistry|March 4, 2010
Design, synthesis, and biological evaluation of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a potent, orally active, brain penetrant inhibitor of phosphodiesterase 5 (PDE5)Robert O Hughes, D Joseph Rogier, E Jon Jacobsen, et al.Journal of Medicinal Chemistry|December 23, 2022
Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4Allyn T Londregan, Karlygash Aitmakhanova, James Bennett, et al.Nature Chemical Biology|May 21, 2024
A chemical probe to modulate human GID4 Pro/N-degron interactionsDominic D G Owens, Matthew E R Maitland, Aliakbar Khalili Yazdi, et al.Bioorganic & Medicinal Chemistry Letters|June 23, 2009
Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitorsDafydd R Owen, John K Walker, E Jon Jacobsen, et al.Biorxiv : the Preprint Server for Biology|February 3, 2025
Enantioselective Protein Affinity Selection Mass Spectrometry (EAS-MS)Xiaoyun Wang, Jianxian Sun, Shabbir Ahmad, et al.Proceedings of the National Academy of Sciences of the United States of America|August 20, 2014
(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cellsDalia Barsyte-Lovejoy, Fengling Li, Menno J Oudhoff, et al.Protein Science : a Publication of the Protein Society|February 4, 2005
Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteinsKaren L Maxwell, David Wildes, Arash Zarrine-Afsar, et al.Nature Methods|June 30, 2015
Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitationEdyta Marcon, Harshika Jain, Anandi Bhattacharya, et al.Nature Reviews. Chemistry|July 5, 2022
CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-findingSuzanne Ackloo, Rima Al-Awar, Rommie E Amaro, et al.Pageof 15