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Science (New York, N.Y.)|November 2, 2021
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19Dafydd R Owen, Charlotte M N Allerton, Annaliesa S Anderson, et al.
Journal of Medicinal Chemistry|April 30, 2024
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, et al.
Nature Methods|November 6, 2007
In situ proteolysis for protein crystallization and structure determinationAiping Dong, Xiaohui Xu, Aled M Edwards, et al.
Journal of Medicinal Chemistry|February 28, 2025
Discovery of Nirmatrelvir (PF-07321332): A Potent, Orally Active Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) Main ProteaseJamison B Tuttle, Christophe Allais, Charlotte M N Allerton, et al.
Journal of Medicinal Chemistry|November 4, 2024
A Target Class Ligandability Evaluation of WD40 Repeat-Containing ProteinsSuzanne Ackloo, Fengling Li, Magda Szewczyk, et al.
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