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Aleem Gangjee

Showing results (101-110 of 132) with videos related to

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Molecules (Basel, Switzerland)|December 6, 2016
Janus Compounds, 5-Chloro-N⁴-methyl-N⁴-aryl-9H-pyrimido[4,5-b]indole-2,4-diamines, Cause Both Microtubule Depolymerizing and Stabilizing EffectsCristina C Rohena, April L Risinger, Ravi Kumar Vyas Devambatla, et al.
Journal of Medicinal Chemistry|November 22, 2013
Discovery of 5-substituted pyrrolo[2,3-d]pyrimidine antifolates as dual-acting inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis: implications of inhibiting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase to ampk activation and antitumor activityShermaine Mitchell-Ryan, Yiqiang Wang, Sudhir Raghavan, et al.
Journal of Medicinal Chemistry|April 16, 2016
Correction to Structure-Activity Profiles of Novel 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α and β and the Proton-Coupled Folate TransporterLalit K Golani, Christina George, Sai Zhao, et al.
Journal of Medicinal Chemistry|January 21, 2010
Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entryLei Wang, Christina Cherian, Sita Kugel Desmoulin, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of antitubulin agents with antiangiogenic activity as single entities with multitarget chemotherapy potentialAleem Gangjee, Roheeth Kumar Pavana, Michael A Ihnat, et al.
Molecular Pharmacology|September 24, 2011
Therapeutic targeting of a novel 6-substituted pyrrolo [2,3-d]pyrimidine thienoyl antifolate to human solid tumors based on selective uptake by the proton-coupled folate transporterSita Kugel Desmoulin, Lei Wang, Eric Hales, et al.
Bioorganic & Medicinal Chemistry Letters|August 16, 2014
Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductaseVidya P Kumar, Jose A Cisneros, Kathleen M Frey, et al.
ACS Medicinal Chemistry Letters|December 20, 2023
Discovery of Tumor-Targeted 6-Methyl Substituted Pemetrexed and Related Antifolates with Selective Loss of RFC TransportKrishna Kaku, Manasa P Ravindra, Nian Tong, et al.
Oncotarget|October 27, 2017
AG488 as a therapy against gliomasJadith Ziegler, Anja Bastian, Megan Lerner, et al.
Molecular Pharmacology|July 6, 2010
Targeting the proton-coupled folate transporter for selective delivery of 6-substituted pyrrolo[2,3-d]pyrimidine antifolate inhibitors of de novo purine biosynthesis in the chemotherapy of solid tumorsSita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, et al.
Pageof 14

Showing results (101-110 of 132) with videos related to

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Pageof 14
Molecules (Basel, Switzerland)|December 6, 2016
Janus Compounds, 5-Chloro-N⁴-methyl-N⁴-aryl-9H-pyrimido[4,5-b]indole-2,4-diamines, Cause Both Microtubule Depolymerizing and Stabilizing EffectsCristina C Rohena, April L Risinger, Ravi Kumar Vyas Devambatla, et al.
Journal of Medicinal Chemistry|November 22, 2013
Discovery of 5-substituted pyrrolo[2,3-d]pyrimidine antifolates as dual-acting inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis: implications of inhibiting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase to ampk activation and antitumor activityShermaine Mitchell-Ryan, Yiqiang Wang, Sudhir Raghavan, et al.
Journal of Medicinal Chemistry|April 16, 2016
Correction to Structure-Activity Profiles of Novel 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α and β and the Proton-Coupled Folate TransporterLalit K Golani, Christina George, Sai Zhao, et al.
Journal of Medicinal Chemistry|January 21, 2010
Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entryLei Wang, Christina Cherian, Sita Kugel Desmoulin, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of antitubulin agents with antiangiogenic activity as single entities with multitarget chemotherapy potentialAleem Gangjee, Roheeth Kumar Pavana, Michael A Ihnat, et al.
Molecular Pharmacology|September 24, 2011
Therapeutic targeting of a novel 6-substituted pyrrolo [2,3-d]pyrimidine thienoyl antifolate to human solid tumors based on selective uptake by the proton-coupled folate transporterSita Kugel Desmoulin, Lei Wang, Eric Hales, et al.
Bioorganic & Medicinal Chemistry Letters|August 16, 2014
Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductaseVidya P Kumar, Jose A Cisneros, Kathleen M Frey, et al.
ACS Medicinal Chemistry Letters|December 20, 2023
Discovery of Tumor-Targeted 6-Methyl Substituted Pemetrexed and Related Antifolates with Selective Loss of RFC TransportKrishna Kaku, Manasa P Ravindra, Nian Tong, et al.
Oncotarget|October 27, 2017
AG488 as a therapy against gliomasJadith Ziegler, Anja Bastian, Megan Lerner, et al.
Molecular Pharmacology|July 6, 2010
Targeting the proton-coupled folate transporter for selective delivery of 6-substituted pyrrolo[2,3-d]pyrimidine antifolate inhibitors of de novo purine biosynthesis in the chemotherapy of solid tumorsSita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, et al.
Pageof 14