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Aleem Gangjee

Showing results (111-120 of 132) with videos related to

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Journal of Medicinal Chemistry|April 28, 2018
Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide BiosynthesisManasa Ravindra, Mike R Wilson, Nian Tong, et al.
The Journal of Pharmacology and Experimental Therapeutics|February 28, 2015
A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancerAnja Bastian, Jessica E Thorpe, Bryan C Disch, et al.
Bioorganic & Medicinal Chemistry Letters|January 9, 2026
Discovery of multitargeting single agents as a novel route to the potential treatment of neurodegenerative diseasesJeetal Vyas, Anuj S Jamenis, Krishna Kaku, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 15, 2025
Pharmacodynamic determinants of mitochondrial one-carbon flux and serine hydroxymethyltransferase inhibition in human tumorsMathew Schneider, Carrie O'Connor, Xun Bao, et al.
The Journal of Pharmacology and Experimental Therapeutics|June 2, 2012
Intestinal transport of aminopterin enantiomers in dogs and humans with psoriasis is stereoselective: evidence for a mechanism involving the proton-coupled folate transporterAlan Menter, Breck Thrash, Christina Cherian, et al.
Journal of Medicinal Chemistry|February 10, 2018
Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3- d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide BiosynthesisManasa Ravindra, Adrianne Wallace-Povirk, Mohammad A Karim, et al.
Molecular Pharmacology|November 11, 2019
Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-<i>d</i>]pyrimidine Inhibitor Targeting Mitochondrial and Cytosolic One-Carbon MetabolismAamod S Dekhne, Changwen Ning, Md Junayed Nayeen, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|March 25, 2026
Determination of the pyrrolo[2,3-d] pyrimidine antifolate AGF94 from a preclinical murine study using a simple UHPLC-MS/MS assayTryston T Metz, Rachel C Ashe, Alexis C Duncan, et al.
Molecular Cancer Therapeutics|February 1, 2017
Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidine AntifolatesZhanjun Hou, Leda Gattoc, Carrie O'Connor, et al.
Bioorganic & Medicinal Chemistry|March 27, 2021
Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumorsAdrianne Wallace-Povirk, Nian Tong, Jennifer Wong-Roushar, et al.
Pageof 14

Showing results (111-120 of 132) with videos related to

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Pageof 14
Journal of Medicinal Chemistry|April 28, 2018
Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide BiosynthesisManasa Ravindra, Mike R Wilson, Nian Tong, et al.
The Journal of Pharmacology and Experimental Therapeutics|February 28, 2015
A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancerAnja Bastian, Jessica E Thorpe, Bryan C Disch, et al.
Bioorganic & Medicinal Chemistry Letters|January 9, 2026
Discovery of multitargeting single agents as a novel route to the potential treatment of neurodegenerative diseasesJeetal Vyas, Anuj S Jamenis, Krishna Kaku, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 15, 2025
Pharmacodynamic determinants of mitochondrial one-carbon flux and serine hydroxymethyltransferase inhibition in human tumorsMathew Schneider, Carrie O'Connor, Xun Bao, et al.
The Journal of Pharmacology and Experimental Therapeutics|June 2, 2012
Intestinal transport of aminopterin enantiomers in dogs and humans with psoriasis is stereoselective: evidence for a mechanism involving the proton-coupled folate transporterAlan Menter, Breck Thrash, Christina Cherian, et al.
Journal of Medicinal Chemistry|February 10, 2018
Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3- d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide BiosynthesisManasa Ravindra, Adrianne Wallace-Povirk, Mohammad A Karim, et al.
Molecular Pharmacology|November 11, 2019
Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-<i>d</i>]pyrimidine Inhibitor Targeting Mitochondrial and Cytosolic One-Carbon MetabolismAamod S Dekhne, Changwen Ning, Md Junayed Nayeen, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|March 25, 2026
Determination of the pyrrolo[2,3-d] pyrimidine antifolate AGF94 from a preclinical murine study using a simple UHPLC-MS/MS assayTryston T Metz, Rachel C Ashe, Alexis C Duncan, et al.
Molecular Cancer Therapeutics|February 1, 2017
Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidine AntifolatesZhanjun Hou, Leda Gattoc, Carrie O'Connor, et al.
Bioorganic & Medicinal Chemistry|March 27, 2021
Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumorsAdrianne Wallace-Povirk, Nian Tong, Jennifer Wong-Roushar, et al.
Pageof 14