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Aleem Gangjee

Showing results (31-40 of 132) with videos related to

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Journal of Medicinal Chemistry|July 9, 2008
The effect of 5-alkyl modification on the biological activity of pyrrolo[2,3-d]pyrimidine containing classical and nonclassical antifolates as inhibitors of dihydrofolate reductase and as antitumor and/or antiopportunistic infection agentsAleem Gangjee, Hiteshkumar D Jain, Sherry F Queener, et al.
Bioorganic & Medicinal Chemistry Letters|March 5, 2017
Synthesis and evaluation of 5-(arylthio)-9H-pyrimido[4,5-b]indole-2,4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agentsNilesh Zaware, Roy Kisliuk, Anja Bastian, et al.
Journal of Medicinal Chemistry|June 15, 2007
Discovery of novel antitumor antimitotic agents that also reverse tumor resistanceAleem Gangjee, Jianming Yu, Jean E Copper, et al.
Molecular Cancer Therapeutics|September 4, 2020
Therapeutic Targeting of Mitochondrial One-Carbon Metabolism in CancerAamod S Dekhne, Zhanjun Hou, Aleem Gangjee, et al.
Bioorganic & Medicinal Chemistry|June 18, 2011
2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistanceAleem Gangjee, Ojas A Namjoshi, Staci N Keller, et al.
Journal of Medicinal Chemistry|July 27, 2011
Synthesis and biological activities of (R)- and (S)-N-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium chloride as potent cytotoxic antitubulin agentsAleem Gangjee, Ying Zhao, Ernest Hamel, et al.
Journal of Medicinal Chemistry|December 24, 2004
Benzoyl ring halogenated classical 2-amino-6-methyl-3,4-dihydro-4-oxo-5-substituted thiobenzoyl-7H-pyrrolo[2,3-d]pyrimidine antifolates as inhibitors of thymidylate synthase and as antitumor agentsAleem Gangjee, Hiteshkumar D Jain, John J McGuire, et al.
Acta Crystallographica. Section D, Biological Crystallography|March 27, 2003
Analysis of two polymorphic forms of a pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolate binary complex with human dihydrofolate reductaseVivian Cody, Nikolai Galitsky, Joseph R Luft, et al.
Journal of Molecular Graphics & Modelling|March 19, 2018
Development and validation of chemical features-based proton-coupled folate transporter/activity and reduced folate carrier/activity models (pharmacophores)Khushbu Shah, Sudhir Raghavan, Zhanjun Hou, et al.
Bioorganic & Medicinal Chemistry|April 16, 2018
Structure based drug design and in vitro metabolism study: Discovery of N-(4-methylthiophenyl)-N,2-dimethyl-cyclopenta[d]pyrimidine as a potent microtubule targeting agentWeiguo Xiang, Shruti Choudhary, Ernest Hamel, et al.
Pageof 14

Showing results (31-40 of 132) with videos related to

Sort By:
Pageof 14
Journal of Medicinal Chemistry|July 9, 2008
The effect of 5-alkyl modification on the biological activity of pyrrolo[2,3-d]pyrimidine containing classical and nonclassical antifolates as inhibitors of dihydrofolate reductase and as antitumor and/or antiopportunistic infection agentsAleem Gangjee, Hiteshkumar D Jain, Sherry F Queener, et al.
Bioorganic & Medicinal Chemistry Letters|March 5, 2017
Synthesis and evaluation of 5-(arylthio)-9H-pyrimido[4,5-b]indole-2,4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agentsNilesh Zaware, Roy Kisliuk, Anja Bastian, et al.
Journal of Medicinal Chemistry|June 15, 2007
Discovery of novel antitumor antimitotic agents that also reverse tumor resistanceAleem Gangjee, Jianming Yu, Jean E Copper, et al.
Molecular Cancer Therapeutics|September 4, 2020
Therapeutic Targeting of Mitochondrial One-Carbon Metabolism in CancerAamod S Dekhne, Zhanjun Hou, Aleem Gangjee, et al.
Bioorganic & Medicinal Chemistry|June 18, 2011
2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistanceAleem Gangjee, Ojas A Namjoshi, Staci N Keller, et al.
Journal of Medicinal Chemistry|July 27, 2011
Synthesis and biological activities of (R)- and (S)-N-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium chloride as potent cytotoxic antitubulin agentsAleem Gangjee, Ying Zhao, Ernest Hamel, et al.
Journal of Medicinal Chemistry|December 24, 2004
Benzoyl ring halogenated classical 2-amino-6-methyl-3,4-dihydro-4-oxo-5-substituted thiobenzoyl-7H-pyrrolo[2,3-d]pyrimidine antifolates as inhibitors of thymidylate synthase and as antitumor agentsAleem Gangjee, Hiteshkumar D Jain, John J McGuire, et al.
Acta Crystallographica. Section D, Biological Crystallography|March 27, 2003
Analysis of two polymorphic forms of a pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolate binary complex with human dihydrofolate reductaseVivian Cody, Nikolai Galitsky, Joseph R Luft, et al.
Journal of Molecular Graphics & Modelling|March 19, 2018
Development and validation of chemical features-based proton-coupled folate transporter/activity and reduced folate carrier/activity models (pharmacophores)Khushbu Shah, Sudhir Raghavan, Zhanjun Hou, et al.
Bioorganic & Medicinal Chemistry|April 16, 2018
Structure based drug design and in vitro metabolism study: Discovery of N-(4-methylthiophenyl)-N,2-dimethyl-cyclopenta[d]pyrimidine as a potent microtubule targeting agentWeiguo Xiang, Shruti Choudhary, Ernest Hamel, et al.
Pageof 14