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Bioorganic & Medicinal Chemistry
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December 30, 2011
N⁴-Aryl-6-substitutedphenylmethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as receptor tyrosine kinase inhibitors
Aleem Gangjee, Sonali Kurup, Michael A Ihnat, et al.
Bioorganic & Medicinal Chemistry
|
June 19, 2010
Design, synthesis and evaluation of 2-amino-4-m-bromoanilino-6-arylmethyl-7H-pyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors and antiangiogenic agents
Aleem Gangjee, Ying Zhao, Sudhir Raghavan, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
March 25, 2004
Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry
Vivian Cody, Joe R Luft, Walt Pangborn, et al.
Journal of Medicinal Chemistry
|
December 24, 2004
Synthesis of classical, three-carbon-bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates
Aleem Gangjee, Yibin Zeng, John J McGuire, et al.
Antimicrobial Agents and Chemotherapy
|
April 3, 2013
Kinetic and structural analysis for potent antifolate inhibition of Pneumocystis jirovecii, Pneumocystis carinii, and human dihydrofolate reductases and their active-site variants
Vivian Cody, Jim Pace, Sherry F Queener, et al.
Bioorganic & Medicinal Chemistry
|
May 10, 2011
Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors
Xin Zhang, Xilin Zhou, Roy L Kisliuk, et al.
Bioorganic & Medicinal Chemistry
|
April 21, 2010
Synthesis and biological activity of N(4)-phenylsubstituted-6-(2,4-dichloro phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic and antitumor agents
Aleem Gangjee, Sonali Kurup, Michael A Ihnat, et al.
Journal of Medicinal Chemistry
|
January 23, 2010
Single agents with designed combination chemotherapy potential: synthesis and evaluation of substituted pyrimido[4,5-b]indoles as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents
Aleem Gangjee, Nilesh Zaware, Sudhir Raghavan, et al.
Cancers
|
January 11, 2022
Folate Transport and One-Carbon Metabolism in Targeted Therapies of Epithelial Ovarian Cancer
Adrianne Wallace-Povirk, Zhanjun Hou, Md Junayed Nayeen, et al.
Bioorganic & Medicinal Chemistry
|
April 26, 2018
Targeting species specific amino acid residues: Design, synthesis and biological evaluation of 6-substituted pyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors and potential anti-opportunistic infection agents
Khushbu Shah, Xin Lin, Sherry F Queener, et al.
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of 14
Search research articles
Search
Showing results (41-50 of 132) with videos related to
Sort By:
Page
of 14
Bioorganic & Medicinal Chemistry
|
December 30, 2011
N⁴-Aryl-6-substitutedphenylmethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as receptor tyrosine kinase inhibitors
Aleem Gangjee, Sonali Kurup, Michael A Ihnat, et al.
Bioorganic & Medicinal Chemistry
|
June 19, 2010
Design, synthesis and evaluation of 2-amino-4-m-bromoanilino-6-arylmethyl-7H-pyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors and antiangiogenic agents
Aleem Gangjee, Ying Zhao, Sudhir Raghavan, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
March 25, 2004
Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry
Vivian Cody, Joe R Luft, Walt Pangborn, et al.
Journal of Medicinal Chemistry
|
December 24, 2004
Synthesis of classical, three-carbon-bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates
Aleem Gangjee, Yibin Zeng, John J McGuire, et al.
Antimicrobial Agents and Chemotherapy
|
April 3, 2013
Kinetic and structural analysis for potent antifolate inhibition of Pneumocystis jirovecii, Pneumocystis carinii, and human dihydrofolate reductases and their active-site variants
Vivian Cody, Jim Pace, Sherry F Queener, et al.
Bioorganic & Medicinal Chemistry
|
May 10, 2011
Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors
Xin Zhang, Xilin Zhou, Roy L Kisliuk, et al.
Bioorganic & Medicinal Chemistry
|
April 21, 2010
Synthesis and biological activity of N(4)-phenylsubstituted-6-(2,4-dichloro phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic and antitumor agents
Aleem Gangjee, Sonali Kurup, Michael A Ihnat, et al.
Journal of Medicinal Chemistry
|
January 23, 2010
Single agents with designed combination chemotherapy potential: synthesis and evaluation of substituted pyrimido[4,5-b]indoles as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents
Aleem Gangjee, Nilesh Zaware, Sudhir Raghavan, et al.
Cancers
|
January 11, 2022
Folate Transport and One-Carbon Metabolism in Targeted Therapies of Epithelial Ovarian Cancer
Adrianne Wallace-Povirk, Zhanjun Hou, Md Junayed Nayeen, et al.
Bioorganic & Medicinal Chemistry
|
April 26, 2018
Targeting species specific amino acid residues: Design, synthesis and biological evaluation of 6-substituted pyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors and potential anti-opportunistic infection agents
Khushbu Shah, Xin Lin, Sherry F Queener, et al.
Page
of 14