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Biochemical Pharmacology
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June 9, 2004
Inhibition of insulin-like growth factor I receptor autophosphorylation by novel 6-5 ring-fused compounds
Wanqing Li, Svetlana Favelyukis, Jie Yang, et al.
Journal of Medicinal Chemistry
|
May 1, 2013
Design, synthesis, and molecular modeling of novel pyrido[2,3-d]pyrimidine analogues as antifolates; application of Buchwald-Hartwig aminations of heterocycles
Aleem Gangjee, Ojas A Namjoshi, Sudhir Raghavan, et al.
Biochemistry
|
February 11, 2017
Correction to Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase
Siobhan M Deis, Arpit Doshi, Zhanjun Hou, et al.
The Biochemical Journal
|
March 28, 2019
Regulation of differential proton-coupled folate transporter gene expression in human tumors: transactivation by KLF15 with NRF-1 and the role of Sp1
Zhanjun Hou, Carrie O'Connor, Josephine Frühauf, et al.
Journal of Medicinal Chemistry
|
February 7, 2003
Design, synthesis, and biological activities of classical N-[4-[2-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid and its 6-methyl derivative as potential dual inhibitors of thymidylate synthase and dihydrofolate reductase and as potential antitumor agents
Aleem Gangjee, Jianming Yu, Roy L Kisliuk, et al.
Bioorganic & Medicinal Chemistry
|
November 5, 2019
Discovery of amide-bridged pyrrolo[2,3-d]pyrimidines as tumor targeted classical antifolates with selective uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesis
Weiguo Xiang, Aamod Dekhne, Arpit Doshi, et al.
Molecular Pharmacology
|
January 10, 2008
Role of lysine 411 in substrate carboxyl group binding to the human reduced folate carrier, as determined by site-directed mutagenesis and affinity inhibition
Yijun Deng, Zhanjun Hou, Lei Wang, et al.
Journal of Medicinal Chemistry
|
January 17, 2012
Synthesis and biological activity of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl regioisomers as inhibitors of de novo purine biosynthesis with selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier
Lei Wang, Christina Cherian, Sita Kugel Desmoulin, et al.
BMC Cancer
|
July 17, 2015
A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model
Rheal A Towner, Michael Ihnat, Debra Saunders, et al.
Bioorganic & Medicinal Chemistry
|
November 30, 2016
Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agents
Roheeth Kumar Pavana, Shruti Choudhary, Anja Bastian, et al.
Page
of 14
Search research articles
Search
Showing results (61-70 of 132) with videos related to
Sort By:
Page
of 14
Biochemical Pharmacology
|
June 9, 2004
Inhibition of insulin-like growth factor I receptor autophosphorylation by novel 6-5 ring-fused compounds
Wanqing Li, Svetlana Favelyukis, Jie Yang, et al.
Journal of Medicinal Chemistry
|
May 1, 2013
Design, synthesis, and molecular modeling of novel pyrido[2,3-d]pyrimidine analogues as antifolates; application of Buchwald-Hartwig aminations of heterocycles
Aleem Gangjee, Ojas A Namjoshi, Sudhir Raghavan, et al.
Biochemistry
|
February 11, 2017
Correction to Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase
Siobhan M Deis, Arpit Doshi, Zhanjun Hou, et al.
The Biochemical Journal
|
March 28, 2019
Regulation of differential proton-coupled folate transporter gene expression in human tumors: transactivation by KLF15 with NRF-1 and the role of Sp1
Zhanjun Hou, Carrie O'Connor, Josephine Frühauf, et al.
Journal of Medicinal Chemistry
|
February 7, 2003
Design, synthesis, and biological activities of classical N-[4-[2-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid and its 6-methyl derivative as potential dual inhibitors of thymidylate synthase and dihydrofolate reductase and as potential antitumor agents
Aleem Gangjee, Jianming Yu, Roy L Kisliuk, et al.
Bioorganic & Medicinal Chemistry
|
November 5, 2019
Discovery of amide-bridged pyrrolo[2,3-d]pyrimidines as tumor targeted classical antifolates with selective uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesis
Weiguo Xiang, Aamod Dekhne, Arpit Doshi, et al.
Molecular Pharmacology
|
January 10, 2008
Role of lysine 411 in substrate carboxyl group binding to the human reduced folate carrier, as determined by site-directed mutagenesis and affinity inhibition
Yijun Deng, Zhanjun Hou, Lei Wang, et al.
Journal of Medicinal Chemistry
|
January 17, 2012
Synthesis and biological activity of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl regioisomers as inhibitors of de novo purine biosynthesis with selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier
Lei Wang, Christina Cherian, Sita Kugel Desmoulin, et al.
BMC Cancer
|
July 17, 2015
A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model
Rheal A Towner, Michael Ihnat, Debra Saunders, et al.
Bioorganic & Medicinal Chemistry
|
November 30, 2016
Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agents
Roheeth Kumar Pavana, Shruti Choudhary, Anja Bastian, et al.
Page
of 14