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Aleem Gangjee

Showing results (81-90 of 132) with videos related to

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Bioorganic & Medicinal Chemistry|February 26, 2013
Synthesis and biological activity of 5-chloro-N⁴-substituted phenyl-9H-pyrimido[4,5-b]indole-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic agentsAleem Gangjee, Nilesh Zaware, Sudhir Raghavan, et al.
Bioorganic & Medicinal Chemistry|June 29, 2012
Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agentsAleem Gangjee, Ying Zhao, Michael A Ihnat, et al.
Journal of Medicinal Chemistry|April 18, 2009
Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entryYijun Deng, Xilin Zhou, Sita Kugel Desmoulin, et al.
Journal of Medicinal Chemistry|January 21, 2015
Novel 5-substituted pyrrolo[2,3-d]pyrimidines as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase and as potential antitumor agentsYiqiang Wang, Shermaine Mitchell-Ryan, Sudhir Raghavan, et al.
Scientific Reports|March 19, 2021
Folate transporter dynamics and therapy with classic and tumor-targeted antifolatesCarrie O'Connor, Adrianne Wallace-Povirk, Changwen Ning, et al.
Bioorganic & Medicinal Chemistry|July 26, 2005
Novel 5-substituted, 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors with antiangiogenic and antitumor activityAleem Gangjee, Yibin Zeng, Michael Ihnat, et al.
Journal of Medicinal Chemistry|October 12, 2013
Tumor-targeting with novel non-benzoyl 6-substituted straight chain pyrrolo[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesisYiqiang Wang, Christina Cherian, Steven Orr, et al.
ACS Medicinal Chemistry Letters|January 29, 2014
Discovery of potent and selective inhibitors of <i>Toxoplasma gondii</i> thymidylate synthase for opportunistic infectionsNilesh Zaware, Hitesh Sharma, Jie Yang, et al.
Bioorganic & Medicinal Chemistry|December 14, 2020
The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activityWeiguo Xiang, Tasdique M Quadery, Ernest Hamel, et al.
Cancer Letters|December 13, 2016
AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilizationAnja Bastian, Satoshi Matsuzaki, Kenneth M Humphries, et al.
Pageof 14

Showing results (81-90 of 132) with videos related to

Sort By:
Pageof 14
Bioorganic & Medicinal Chemistry|February 26, 2013
Synthesis and biological activity of 5-chloro-N⁴-substituted phenyl-9H-pyrimido[4,5-b]indole-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic agentsAleem Gangjee, Nilesh Zaware, Sudhir Raghavan, et al.
Bioorganic & Medicinal Chemistry|June 29, 2012
Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agentsAleem Gangjee, Ying Zhao, Michael A Ihnat, et al.
Journal of Medicinal Chemistry|April 18, 2009
Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entryYijun Deng, Xilin Zhou, Sita Kugel Desmoulin, et al.
Journal of Medicinal Chemistry|January 21, 2015
Novel 5-substituted pyrrolo[2,3-d]pyrimidines as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase and as potential antitumor agentsYiqiang Wang, Shermaine Mitchell-Ryan, Sudhir Raghavan, et al.
Scientific Reports|March 19, 2021
Folate transporter dynamics and therapy with classic and tumor-targeted antifolatesCarrie O'Connor, Adrianne Wallace-Povirk, Changwen Ning, et al.
Bioorganic & Medicinal Chemistry|July 26, 2005
Novel 5-substituted, 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors with antiangiogenic and antitumor activityAleem Gangjee, Yibin Zeng, Michael Ihnat, et al.
Journal of Medicinal Chemistry|October 12, 2013
Tumor-targeting with novel non-benzoyl 6-substituted straight chain pyrrolo[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesisYiqiang Wang, Christina Cherian, Steven Orr, et al.
ACS Medicinal Chemistry Letters|January 29, 2014
Discovery of potent and selective inhibitors of <i>Toxoplasma gondii</i> thymidylate synthase for opportunistic infectionsNilesh Zaware, Hitesh Sharma, Jie Yang, et al.
Bioorganic & Medicinal Chemistry|December 14, 2020
The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activityWeiguo Xiang, Tasdique M Quadery, Ernest Hamel, et al.
Cancer Letters|December 13, 2016
AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilizationAnja Bastian, Satoshi Matsuzaki, Kenneth M Humphries, et al.
Pageof 14