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JACS Au|May 13, 2022
Expanded LUXendin Color Palette for GLP1R Detection and Visualization In Vitro and In VivoJulia Ast, Alissa N Novak, Tom Podewin, et al.
Diabetes, Obesity & Metabolism|June 9, 2022
In vivo and in vitro characterization of GL0034, a novel long-acting glucagon-like peptide-1 receptor agonistBen Jones, Vinod Burade, Elina Akalestou, et al.
Biochemical Pharmacology|June 15, 2021
Evaluation of efficacy- versus affinity-driven agonism with biased GLP-1R ligands P5 and exendin-F1Amaara Marzook, Shiqian Chen, Phil Pickford, et al.
Diabetes|December 30, 2017
A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-CellsTeresa Buenaventura, Nisha Kanda, Phoebe C Douzenis, et al.
ACS Pharmacology & Translational Science|April 17, 2020
The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased AgonistsZijian Fang, Shiqian Chen, Philip Pickford, et al.
Molecular Metabolism|May 14, 2021
Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetesDaniel S de Jesus, Tracy C S Mak, Yi-Fang Wang, et al.
Molecular Metabolism|December 14, 2025
Spatially diffuse cAMP signalling with oppositely biased GLP-1 receptor agonists in β-cells despite differences in receptor localisationShiqian Chen, Carolina B Lobato, Carissa Wong, et al.
The Journal of Biological Chemistry|December 3, 2020
Genetic and biased agonist-mediated reductions in β-arrestin recruitment prolong cAMP signaling at glucagon family receptorsBen Jones, Emma Rose McGlone, Zijian Fang, et al.
Molecular Metabolism|May 2, 2021
Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonistPhil Pickford, Maria Lucey, Roxana-Maria Rujan, et al.
ACS Central Science|March 14, 2018
Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered PharmacologyTom Podewin, Julia Ast, Johannes Broichhagen, et al.
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