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European Stroke Journal|March 12, 2025
Feasibility of telephone and computerized cognitive testing as a secondary outcome in an acute stroke clinical trial: A mixed methods sub-study of the AcT TrialSajeevan Sujanthan, Pugaliya Puveendrakumaran, Katie N Dainty, et al.
Lancet (London, England)|February 15, 2025
Efficacy and safety of intravenous nerinetide initiated by paramedics in the field for acute cerebral ischaemia within 3 h of symptom onset (FRONTIER): a phase 2, multicentre, randomised, double-blind, placebo-controlled studyJim Christenson, Michael D Hill, Richard H Swartz, et al.
Stroke and Vascular Neurology|January 31, 2024
Intravenous tenecteplase compared with alteplase for minor ischaemic stroke: a secondary analysis of the AcT randomised clinical trialRadhika Nair, Nishita Singh, Mahesh Kate, et al.
Stroke|July 18, 2025
Faster Thrombolysis Is Associated With Improved Cognitive Outcomes in Patients With Acute Ischemic Stroke Treated With Alteplase and Tenecteplase: A Substudy of the AcT TrialSajeevan Sujanthan, Gayathiri Rajkumar, Katie N Dainty, et al.
Stroke (Hoboken, N.J.)|May 8, 2026
AcT Trial: Protocol for a Pragmatic Registry-Linked Randomized Clinical TrialTolulope Sajobi, Nishita Singh, Mohammed A Almekhlafi, et al.
The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques|August 8, 2025
The Acute Stroke System of Treatment Across Canada: Findings from a National Stroke Centre SurveyBetty Adewusi, Andrew M Demchuk, Grant Stotts, et al.
Stroke|March 24, 2025
Safety, Functional Disability, Healthcare Utilization, and Quality-of-Life Outcomes in Elderly Receiving Alteplase and Tenecteplase: A Secondary Analysis From the AcT TrialNishita Singh, Fouzi Bala, Ayoola Ademola, et al.
JAMA Neurology|July 10, 2023
Safety and Efficacy of Tenecteplase Compared With Alteplase in Patients With Large Vessel Occlusion Stroke: A Prespecified Secondary Analysis of the ACT Randomized Clinical TrialFouzi Bala, Nishita Singh, Brian Buck, et al.
International Journal of Stroke : Official Journal of the International Stroke Society|September 21, 2023
Safety and efficacy of tenecteplase versus alteplase in stroke patients with carotid tandem lesions: Results from the AcT trialFouzi Bala, Mohammed Almekhlafi, Nishita Singh, et al.
Stroke|October 6, 2023
Effect of Time to Thrombolysis on Clinical Outcomes in Patients With Acute Ischemic Stroke Treated With Tenecteplase Compared to Alteplase: Analysis From the AcT Randomized Controlled TrialNishita Singh, Mohammed A Almekhlafi, Fouzi Bala, et al.
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