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Neurobiology of Disease|March 21, 2008
Study of subcellular localization and proteolysis of ataxin-3Chiara Pozzi, Marco Valtorta, Gabriella Tedeschi, et al.Communications Biology|March 28, 2026
Engineering a dimeric single-domain antibody for improved detection and neutralization of amyloid-β oligomersLiliana Napolitano, Devkee M Vadukul, Alessandra Bigi, et al.Cell & Bioscience|December 9, 2025
Cellular prion protein and calcium ions trigger the neurotoxicity of α-synuclein aggregatesAlessandra Bigi, Andrea Carlotta Conti, Liliana Napolitano, et al.Science Advances|July 27, 2022
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43Roberta Cascella, Alessandra Bigi, Dylan Giorgino Riffert, et al.Nature Communications|March 23, 2021
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cellsRoberta Cascella, Serene W Chen, Alessandra Bigi, et al.Iscience|May 2, 2023
APP and Bace1: Differential effect of cholesterol enrichment on processing and plasma membrane mobilityClaudia Capitini, Alessandra Bigi, Niccolò Parenti, et al.The FEBS Journal|May 2, 2026
Unraveling in vitro phase separation and aggregation properties of the structured region of FMRP and the impact of Fragile X syndrome-linked mutationsFlavia Catalano, Alessandra Bigi, Francesca Troilo, et al.Journal of the American Chemical Society|April 3, 2024
Structure-Toxicity Relationship in Intermediate Fibrils from α-Synuclein CondensatesSerene W Chen, Joseph D Barritt, Roberta Cascella, et al.The FEBS Journal|March 29, 2019
The acute myeloid leukemia-associated Nucleophosmin 1 gene mutations dictate amyloidogenicity of the C-terminal domainSara La Manna, Pasqualina Liana Scognamiglio, Valentina Roviello, et al.Annals of Medicine|December 10, 2022
An <i>in situ</i> and <i>in vitro</i> investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signatureRoberta Cascella, Martina Banchelli, Seyyed Abolghasem Ghadami, et al.Pageof 4