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Bioorganic Chemistry
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June 29, 2026
Rational design and synthesis of pyrazole-based sulfonamides as dual carbonic anhydrase and PRAK-targeting anticancer agents
Mariam M Fakhry, Mohamed A Said, Noha Zeidan, et al.
European Journal of Medicinal Chemistry
|
October 20, 2019
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights
Mahmoud F Abo-Ashour, Wagdy M Eldehna, Alessio Nocentini, et al.
Cells
|
October 23, 2021
Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats
Elena Lucarini, Alessio Nocentini, Alessandro Bonardi, et al.
Bioorganic Chemistry
|
July 13, 2019
Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activity
Wagdy M Eldehna, Mohamed A Abdelrahman, Alessio Nocentini, et al.
European Journal of Medicinal Chemistry
|
November 17, 2018
Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents
Wagdy M Eldehna, Mahmoud F Abo-Ashour, Alessio Nocentini, et al.
European Journal of Medicinal Chemistry
|
February 16, 2023
4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessments
Mahmoud A Ragab, Wagdy M Eldehna, Alessio Nocentini, et al.
Journal of Medicinal Chemistry
|
April 29, 2026
Discovery of a Mixed and Prodrug-Like Inhibition Mechanism for Phosphocoumarins and Phosphoquinolinones against Human Carbonic Anhydrases
Alessio Nocentini, Simone Giovannuzzi, Vincenzo Alterio, et al.
European Journal of Medicinal Chemistry
|
January 24, 2020
Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation
Mohamed A Said, Wagdy M Eldehna, Alessio Nocentini, et al.
Journal of Medicinal Chemistry
|
November 17, 2024
4-(Pyrazolyl)benzenesulfonamide Ureas as Carbonic Anhydrases Inhibitors and Hypoxia-Mediated Chemo-Sensitizing Agents in Colorectal Cancer Cells
Wagdy M Eldehna, Mohamed Fares, Alessandro Bonardi, et al.
European Journal of Medicinal Chemistry
|
April 11, 2018
2-Benzylpiperazine: A new scaffold for potent human carbonic anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents
Niccolò Chiaramonte, Silvia Bua, Marta Ferraroni, et al.
Page
of 11
Search research articles
Search
Showing results (91-100 of 109) with videos related to
Sort By:
Page
of 11
Bioorganic Chemistry
|
June 29, 2026
Rational design and synthesis of pyrazole-based sulfonamides as dual carbonic anhydrase and PRAK-targeting anticancer agents
Mariam M Fakhry, Mohamed A Said, Noha Zeidan, et al.
European Journal of Medicinal Chemistry
|
October 20, 2019
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights
Mahmoud F Abo-Ashour, Wagdy M Eldehna, Alessio Nocentini, et al.
Cells
|
October 23, 2021
Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats
Elena Lucarini, Alessio Nocentini, Alessandro Bonardi, et al.
Bioorganic Chemistry
|
July 13, 2019
Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activity
Wagdy M Eldehna, Mohamed A Abdelrahman, Alessio Nocentini, et al.
European Journal of Medicinal Chemistry
|
November 17, 2018
Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents
Wagdy M Eldehna, Mahmoud F Abo-Ashour, Alessio Nocentini, et al.
European Journal of Medicinal Chemistry
|
February 16, 2023
4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessments
Mahmoud A Ragab, Wagdy M Eldehna, Alessio Nocentini, et al.
Journal of Medicinal Chemistry
|
April 29, 2026
Discovery of a Mixed and Prodrug-Like Inhibition Mechanism for Phosphocoumarins and Phosphoquinolinones against Human Carbonic Anhydrases
Alessio Nocentini, Simone Giovannuzzi, Vincenzo Alterio, et al.
European Journal of Medicinal Chemistry
|
January 24, 2020
Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation
Mohamed A Said, Wagdy M Eldehna, Alessio Nocentini, et al.
Journal of Medicinal Chemistry
|
November 17, 2024
4-(Pyrazolyl)benzenesulfonamide Ureas as Carbonic Anhydrases Inhibitors and Hypoxia-Mediated Chemo-Sensitizing Agents in Colorectal Cancer Cells
Wagdy M Eldehna, Mohamed Fares, Alessandro Bonardi, et al.
European Journal of Medicinal Chemistry
|
April 11, 2018
2-Benzylpiperazine: A new scaffold for potent human carbonic anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents
Niccolò Chiaramonte, Silvia Bua, Marta Ferraroni, et al.
Page
of 11