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Cancer Immunology Research|July 19, 2024
MR1 Gene and Protein Expression Are Enhanced by Inhibition of the Extracellular Signal-Regulated Kinase ERKDaniel Constantin, Vladimir Nosi, Natalie Kehrer, et al.Science Signaling|May 2, 2013
β-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6Elena M Borroni, Cinzia Cancellieri, Alessandro Vacchini, et al.Frontiers in Molecular Biosciences|December 9, 2022
Phosphoproteomic mapping of CCR5 and ACKR2 signaling propertiesAlessandro Vacchini, Elisa Maffioli, Dario Di Silvestre, et al.Clinical and Experimental Immunology|August 16, 2023
Surface protein and functional analyses identify CD4+CD39+ TCR αβ+ and activated TCR Vδ1+ cells with distinct pro-inflammatory functions in Crohn's disease lesionsJan Devan, Vladimir Nosi, Julian Spagnuolo, et al.Proceedings of the National Academy of Sciences of the United States of America|May 12, 2025
Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cellsGennaro Prota, Giuliano Berloffa, Wael Awad, et al.Frontiers in Immunology|March 5, 2025
Recognition of MR1-antigen complexes by TCR Vγ9Vδ2José Pedro Loureiro, Alessandro Vacchini, Giuliano Berloffa, et al.Science Signaling|March 10, 2021
Endogenous modification of the chemoattractant CXCL5 alters receptor usage and enhances its activity toward neutrophils and monocytesMieke Metzemaekers, Anneleen Mortier, Alessandro Vacchini, et al.JCI Insight|March 8, 2023
Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndromeRajesh Kumar, Samantha Milanesi, Martyna Szpakowska, et al.Immunity|December 19, 2024
The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cellsAndrew Chancellor, Daniel Constantin, Giuliano Berloffa, et al.Science Immunology|May 10, 2024
Nucleobase adducts bind MR1 and stimulate MR1-restricted T cellsAlessandro Vacchini, Andrew Chancellor, Qinmei Yang, et al.Pageof 3