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Cell Reports|June 21, 2016
A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch RecombinationPedro P Rocha, Ramya Raviram, Yi Fu, et al.Journal of Medicinal Chemistry|March 22, 2021
Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron MicroscopyJack A Terrett, Huifen Chen, Daniel G Shore, et al.Journal of Medicinal Chemistry|March 3, 2024
Discovery of TRPA1 Antagonist GDC-6599: Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory DiseaseJack A Terrett, Justin Q Ly, Paula Katavolos, et al.The Journal of Experimental Medicine|February 23, 2021
A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatmentAlessia Balestrini, Victory Joseph, Michelle Dourado, et al.Pageof 2