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Cell Reports|January 8, 2025
Metabolic reprogramming of macrophages by PKM2 promotes IL-10 production via adenosineJuliana Escher Toller-Kawahisa, Paula Ramos Viacava, Eva Margareta Palsson-McDermott, et al.
Nature Communications|July 17, 2023
The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophilsJuliana Escher Toller-Kawahisa, Carlos Hiroji Hiroki, Camila Meirelles de Souza Silva, et al.
Cell Metabolism|March 2, 2022
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophagesMarah C Runtsch, Stefano Angiari, Alexander Hooftman, et al.
Nature Communications|June 14, 2023
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I InterferonTristram A J Ryan, Alexander Hooftman, Aisling M Rehill, et al.
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