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ACS Medicinal Chemistry Letters|January 18, 2014
Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions?David M Dias, Inge Van Molle, Matthias G J Baud, et al.Nature Chemical Biology|March 14, 2017
Structural basis of PROTAC cooperative recognition for selective protein degradationMorgan S Gadd, Andrea Testa, Xavier Lucas, et al.The Biochemical Journal|March 31, 2017
The biochemical properties of the two Arabidopsis thaliana isochorismate synthasesKeith M Macaulay, Geraldine A Heath, Alessio Ciulli, et al.Journal of Medicinal Chemistry|August 31, 2017
Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)Pedro Soares, Morgan S Gadd, Julianty Frost, et al.Structure (London, England : 1993)|December 24, 2014
Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRCCynthia Tallant, Erica Valentini, Oleg Fedorov, et al.Journal of the American Chemical Society|March 12, 2009
N to C aryl migration in lithiated carbamates: alpha-arylation of benzylic alcoholsJonathan Clayden, William Farnaby, Damian M Grainger, et al.Science Advances|October 11, 2024
Mechanism of degrader-targeted protein ubiquitinabilityCharlotte Crowe, Mark A Nakasone, Sarah Chandler, et al.Nature Communications|October 12, 2017
Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradationChiara Maniaci, Scott J Hughes, Andrea Testa, et al.Chemmedchem|October 22, 2015
Optimization of Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase Based on Group Efficiency AnalysisAlvin W Hung, H Leonardo Silvestre, Shijun Wen, et al.Journal of Medicinal Chemistry|August 29, 2014
Structure-guided design and optimization of small molecules targeting the protein-protein interaction between the von Hippel-Lindau (VHL) E3 ubiquitin ligase and the hypoxia inducible factor (HIF) alpha subunit with in vitro nanomolar affinitiesCarles Galdeano, Morgan S Gadd, Pedro Soares, et al.Pageof 16