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Nature Communications|July 15, 2026
Induced ubiquitination of the partially disordered estrogen receptor alpha via a 14-3-3 directed molecular glue-PROTACCarlo J A Verhoef, Charlotte Crowe, Mark A Nakasone, et al.Oncogene|May 7, 2021
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanomaSilvia Pietrobono, Eugenio Gaudio, Sinforosa Gagliardi, et al.Science (New York, N.Y.)|September 19, 2024
Targeting cancer with small-molecule pan-KRAS degradersJohannes Popow, William Farnaby, Andreas Gollner, et al.British Journal of Pharmacology|April 6, 2017
Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approachAli Ryan, Elena Polycarpou, Nathan A Lack, et al.Nature Communications|June 30, 2026
Targeted Protein Degradation of NUDT5 Dissociates Catalytic Inhibition from Protein Loss in 6-Thioguanine ResponseAnne-Sophie M C Marques, Ludwig G Bauer, Tuan-Anh Nguyen, et al.Scientific Reports|October 14, 2020
Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in miceToshiya Nishi, Shinichi Kondo, Maki Miyamoto, et al.The Biochemical Journal|November 19, 2015
Biophysical characterization of laforin-carbohydrate interactionDavid M Dias, Joana Furtado, Emeric Wasielewski, et al.Nature Chemical Biology|May 12, 2026
Dual E3 ligase recruitment by monovalent degraders for tunable SMARCA 2/4 degradationValentina A Spiteri, Dmitri Segal, Alejandro Correa-Sáez, et al.Biorxiv : the Preprint Server for Biology|April 8, 2025
A method for the detection and enrichment of endogenous cereblon substratesHannah C Lloyd, Yuli Li, N Connor Payne, et al.Cell Chemical Biology|August 9, 2025
A method for the detection and enrichment of endogenous cereblon substratesHannah C Lloyd, Yuli Li, N Connor Payne, et al.Pageof 16