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Current Opinion in Chemical Biology|July 17, 2016
Chemical genetics approaches for selective intervention in epigeneticsAndrew C Runcie, Kwok-Ho Chan, Michael Zengerle, et al.The Biochemical Journal|March 26, 2017
Structural basis of molecular recognition of helical histone H3 tail by PHD finger domainsAlessio Bortoluzzi, Anastasia Amato, Xavier Lucas, et al.Trends in Biochemical Sciences|July 31, 2026
Linkerology in PROTACs: learnings for proximity-inducing therapeuticsRubén Prieto-Díaz, Aina Urbina, María Rodríguez-Ríos, et al.Biochemistry|July 11, 2013
Multimeric complexes among ankyrin-repeat and SOCS-box protein 9 (ASB9), ElonginBC, and Cullin 5: insights into the structure and assembly of ECS-type Cullin-RING E3 ubiquitin ligasesJemima C Thomas, Dijana Matak-Vinkovic, Inge Van Molle, et al.Bioorganic & Medicinal Chemistry|March 4, 2019
Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACsMiriam Girardini, Chiara Maniaci, Scott J Hughes, et al.Journal of the American Chemical Society|April 10, 2025
Rational Design of PROTAC Linkers Featuring Ferrocene as a Molecular Hinge to Enable Dynamic Conformational ChangesAlessandra Salerno, Lianne H E Wieske, Claudia J Diehl, et al.Nature Communications|June 12, 2019
Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligaseWei-Wei Kung, Sarath Ramachandran, Nikolai Makukhin, et al.Nature Communications|September 29, 2025
Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexesNing Ma, Supriyo Bhattacharya, Sanychen Muk, et al.Angewandte Chemie (International Ed. in English)|November 21, 2019
Structure-Based Design of a Macrocyclic PROTACAndrea Testa, Scott J Hughes, Xavier Lucas, et al.ACS Medicinal Chemistry Letters|February 19, 2025
Use of Aldehyde-Alkyne-Amine Couplings to Generate Medicinal Chemistry-Relevant LinkersAndrew McGown, Vesna Vetma, Damien Crepin, et al.Pageof 16