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Journal of Medicinal Chemistry|August 4, 2006
Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methodsAlessio Ciulli, Glyn Williams, Alison G Smith, et al.Chembiochem : a European Journal of Chemical Biology|October 15, 2009
A fragment-based approach to probing adenosine recognition sites by using dynamic combinatorial chemistryDuncan E Scott, Gwen J Dawes, Michiyo Ando, et al.Nature Communications|October 15, 2024
Design of a Cereblon construct for crystallographic and biophysical studies of protein degradersAlena Kroupova, Valentina A Spiteri, Zoe J Rutter, et al.Organic Letters|April 22, 2010
Synthesis of (-)-(S,S)-clemastine by invertive N --> C aryl migration in a lithiated carbamateAnne M Fournier, Robert A Brown, William Farnaby, et al.Journal of Medicinal Chemistry|December 9, 2021
Amide-to-Ester Substitution as a Strategy for Optimizing PROTAC Permeability and Cellular ActivityVictoria G Klein, Adam G Bond, Conner Craigon, et al.Journal of Medicinal Chemistry|September 15, 2015
New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain InhibitionMatthias G J Baud, Enrique Lin-Shiao, Michael Zengerle, et al.The Journal of Biological Chemistry|January 19, 2007
Crystal structure of Escherichia coli ketopantoate reductase in a ternary complex with NADP+ and pantoate bound: substrate recognition, conformational change, and cooperativityAlessio Ciulli, Dimitri Y Chirgadze, Alison G Smith, et al.Bioorganic & Medicinal Chemistry Letters|June 28, 2024
Stereochemical inversion at a 1,4-cyclohexyl PROTAC linker fine-tunes conformation and binding affinityMartina Pierri, Xingui Liu, Alena Kroupova, et al.Journal of Medicinal Chemistry|February 10, 2017
Targeting Bacillosamine Biosynthesis in Bacterial Pathogens: Development of Inhibitors to a Bacterial Amino-Sugar Acetyltransferase from Campylobacter jejuniJoris W De Schutter, James P Morrison, Michael J Morrison, et al.Methods in Molecular Biology (Clifton, N.J.)|August 9, 2023
HiBiT Cellular Thermal Shift Assay (HiBiT CETSA)Sarath Ramachandran, Magdalena Szewczyk, Samir H Barghout, et al.Pageof 16