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Alessio Ciulli

Showing results (91-100 of 148) with videos related to

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EMBO Reports|June 8, 2017
Brd4-Brd2 isoform switching coordinates pluripotent exit and Smad2-dependent lineage specificationRosalia Fernandez-Alonso, Lindsay Davidson, Jens Hukelmann, et al.
Nature Communications|October 10, 2023
Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2Sarath Ramachandran, Nikolai Makukhin, Kevin Haubrich, et al.
The Journal of Biological Chemistry|December 16, 2014
Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2)Emil Bulatov, Esther M Martin, Sneha Chatterjee, et al.
ACS Medicinal Chemistry Letters|September 17, 2020
Understanding and Improving the Membrane Permeability of VH032-Based PROTACsVictoria G Klein, Chad E Townsend, Andrea Testa, et al.
Nature Chemical Biology|November 4, 2022
Functional E3 ligase hotspots and resistance mechanisms to small-molecule degradersAlexander Hanzl, Ryan Casement, Hana Imrichova, et al.
Journal of Medicinal Chemistry|October 15, 2021
Development of BromoTag: A "Bump-and-Hole"-PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target ProteinsAdam G Bond, Conner Craigon, Kwok-Ho Chan, et al.
Journal of the American Chemical Society|February 29, 2012
Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules to disrupt the VHL/HIF-1α interactionDennis L Buckley, Inge Van Molle, Peter C Gareiss, et al.
Journal of Medicinal Chemistry|December 13, 2018
Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7Vittoria Zoppi, Scott J Hughes, Chiara Maniaci, et al.
Biochemistry|October 1, 2014
Binding hotspots of BAZ2B bromodomain: Histone interaction revealed by solution NMR driven dockingFleur M Ferguson, David M Dias, João P G L M Rodrigues, et al.
Cell Chemical Biology|July 16, 2020
Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile SystemLuke M Simpson, Thomas J Macartney, Alice Nardin, et al.
Pageof 15

Showing results (91-100 of 148) with videos related to

Sort By:
Pageof 15
EMBO Reports|June 8, 2017
Brd4-Brd2 isoform switching coordinates pluripotent exit and Smad2-dependent lineage specificationRosalia Fernandez-Alonso, Lindsay Davidson, Jens Hukelmann, et al.
Nature Communications|October 10, 2023
Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2Sarath Ramachandran, Nikolai Makukhin, Kevin Haubrich, et al.
The Journal of Biological Chemistry|December 16, 2014
Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2)Emil Bulatov, Esther M Martin, Sneha Chatterjee, et al.
ACS Medicinal Chemistry Letters|September 17, 2020
Understanding and Improving the Membrane Permeability of VH032-Based PROTACsVictoria G Klein, Chad E Townsend, Andrea Testa, et al.
Nature Chemical Biology|November 4, 2022
Functional E3 ligase hotspots and resistance mechanisms to small-molecule degradersAlexander Hanzl, Ryan Casement, Hana Imrichova, et al.
Journal of Medicinal Chemistry|October 15, 2021
Development of BromoTag: A "Bump-and-Hole"-PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target ProteinsAdam G Bond, Conner Craigon, Kwok-Ho Chan, et al.
Journal of the American Chemical Society|February 29, 2012
Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules to disrupt the VHL/HIF-1α interactionDennis L Buckley, Inge Van Molle, Peter C Gareiss, et al.
Journal of Medicinal Chemistry|December 13, 2018
Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7Vittoria Zoppi, Scott J Hughes, Chiara Maniaci, et al.
Biochemistry|October 1, 2014
Binding hotspots of BAZ2B bromodomain: Histone interaction revealed by solution NMR driven dockingFleur M Ferguson, David M Dias, João P G L M Rodrigues, et al.
Cell Chemical Biology|July 16, 2020
Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile SystemLuke M Simpson, Thomas J Macartney, Alice Nardin, et al.
Pageof 15