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Molecular Biosystems
|
August 2, 2011
Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery
Martin Philpott, Jing Yang, Tony Tumber, et al.
Journal of Medicinal Chemistry
|
December 6, 2013
Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain
Fleur M Ferguson, Oleg Fedorov, Apirat Chaikuad, et al.
Journal of Medicinal Chemistry
|
September 14, 2023
Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α Stabilizers
Lan Phuong Vu, Claudia J Diehl, Ryan Casement, et al.
Chemmedchem
|
June 11, 2021
The 2<sup>nd</sup> Alpine Winter Conference on Medicinal and Synthetic Chemistry
Alessio Ciulli, Lawrence Hamann, Wolfgang Jahnke, et al.
Chemmedchem
|
August 30, 2022
Discovery of Benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain
Alessandra Cipriano, Ciro Milite, Alessandra Feoli, et al.
Journal of the American Chemical Society
|
November 28, 2024
Leveraging Dual-Ligase Recruitment to Enhance Protein Degradation via a Heterotrivalent Proteolysis Targeting Chimera
Adam G Bond, Miquel Muñoz I Ordoño, Celia M Bisbach, et al.
The Biochemical Journal
|
March 18, 2011
Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis
Marcio V B Dias, William C Snee, Karen M Bromfield, et al.
Journal of the American Chemical Society
|
August 25, 2022
Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood-Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2
Xingui Liu, Alexia F Kalogeropulou, Sofia Domingos, et al.
Cell Chemical Biology
|
January 4, 2025
The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells
Gernot Wolf, Conner Craigon, Shao Thing Teoh, et al.
Exploration of Targeted Anti-Tumor Therapy
|
September 1, 2022
The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like type
Chiara Tarantelli, Eleonora Cannas, Hillarie Ekeh, et al.
Page
of 15
Search research articles
Search
Showing results (101-110 of 148) with videos related to
Sort By:
Page
of 15
Molecular Biosystems
|
August 2, 2011
Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery
Martin Philpott, Jing Yang, Tony Tumber, et al.
Journal of Medicinal Chemistry
|
December 6, 2013
Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain
Fleur M Ferguson, Oleg Fedorov, Apirat Chaikuad, et al.
Journal of Medicinal Chemistry
|
September 14, 2023
Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α Stabilizers
Lan Phuong Vu, Claudia J Diehl, Ryan Casement, et al.
Chemmedchem
|
June 11, 2021
The 2<sup>nd</sup> Alpine Winter Conference on Medicinal and Synthetic Chemistry
Alessio Ciulli, Lawrence Hamann, Wolfgang Jahnke, et al.
Chemmedchem
|
August 30, 2022
Discovery of Benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain
Alessandra Cipriano, Ciro Milite, Alessandra Feoli, et al.
Journal of the American Chemical Society
|
November 28, 2024
Leveraging Dual-Ligase Recruitment to Enhance Protein Degradation via a Heterotrivalent Proteolysis Targeting Chimera
Adam G Bond, Miquel Muñoz I Ordoño, Celia M Bisbach, et al.
The Biochemical Journal
|
March 18, 2011
Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis
Marcio V B Dias, William C Snee, Karen M Bromfield, et al.
Journal of the American Chemical Society
|
August 25, 2022
Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood-Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2
Xingui Liu, Alexia F Kalogeropulou, Sofia Domingos, et al.
Cell Chemical Biology
|
January 4, 2025
The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells
Gernot Wolf, Conner Craigon, Shao Thing Teoh, et al.
Exploration of Targeted Anti-Tumor Therapy
|
September 1, 2022
The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like type
Chiara Tarantelli, Eleonora Cannas, Hillarie Ekeh, et al.
Page
of 15