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Journal of the American Chemical Society
|
June 28, 2018
3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation
Andrea Testa, Xavier Lucas, Guilherme V Castro, et al.
Science (New York, N.Y.)
|
October 18, 2014
Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes
Matthias G J Baud, Enrique Lin-Shiao, Teresa Cardote, et al.
Leukemia
|
March 12, 2025
Loss of Socs2 improves molecular responses to IFNα in a mouse model of myeloproliferative neoplasms driven by JAK2-V617F
Marc Usart, Quentin Kimmerlin, Jan Stetka, et al.
Nature Communications
|
November 5, 2016
Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition
Julianty Frost, Carles Galdeano, Pedro Soares, et al.
Oncogene
|
May 7, 2021
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma
Silvia Pietrobono, Eugenio Gaudio, Sinforosa Gagliardi, et al.
Nature Communications
|
July 15, 2026
Induced ubiquitination of the partially disordered estrogen receptor alpha via a 14-3-3 directed molecular glue-PROTAC
Carlo J A Verhoef, Charlotte Crowe, Mark A Nakasone, et al.
British Journal of Pharmacology
|
April 6, 2017
Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach
Ali Ryan, Elena Polycarpou, Nathan A Lack, et al.
Nature Communications
|
June 30, 2026
Targeted Protein Degradation of NUDT5 Dissociates Catalytic Inhibition from Protein Loss in 6-Thioguanine Response
Anne-Sophie M C Marques, Ludwig G Bauer, Tuan-Anh Nguyen, et al.
Nature Chemical Biology
|
May 12, 2026
Dual E3 ligase recruitment by monovalent degraders for tunable SMARCA 2/4 degradation
Valentina A Spiteri, Dmitri Segal, Alejandro Correa-Sáez, et al.
The Biochemical Journal
|
November 19, 2015
Biophysical characterization of laforin-carbohydrate interaction
David M Dias, Joana Furtado, Emeric Wasielewski, et al.
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Search research articles
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Showing results (111-120 of 148) with videos related to
Sort By:
Page
of 15
Journal of the American Chemical Society
|
June 28, 2018
3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation
Andrea Testa, Xavier Lucas, Guilherme V Castro, et al.
Science (New York, N.Y.)
|
October 18, 2014
Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes
Matthias G J Baud, Enrique Lin-Shiao, Teresa Cardote, et al.
Leukemia
|
March 12, 2025
Loss of Socs2 improves molecular responses to IFNα in a mouse model of myeloproliferative neoplasms driven by JAK2-V617F
Marc Usart, Quentin Kimmerlin, Jan Stetka, et al.
Nature Communications
|
November 5, 2016
Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition
Julianty Frost, Carles Galdeano, Pedro Soares, et al.
Oncogene
|
May 7, 2021
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma
Silvia Pietrobono, Eugenio Gaudio, Sinforosa Gagliardi, et al.
Nature Communications
|
July 15, 2026
Induced ubiquitination of the partially disordered estrogen receptor alpha via a 14-3-3 directed molecular glue-PROTAC
Carlo J A Verhoef, Charlotte Crowe, Mark A Nakasone, et al.
British Journal of Pharmacology
|
April 6, 2017
Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach
Ali Ryan, Elena Polycarpou, Nathan A Lack, et al.
Nature Communications
|
June 30, 2026
Targeted Protein Degradation of NUDT5 Dissociates Catalytic Inhibition from Protein Loss in 6-Thioguanine Response
Anne-Sophie M C Marques, Ludwig G Bauer, Tuan-Anh Nguyen, et al.
Nature Chemical Biology
|
May 12, 2026
Dual E3 ligase recruitment by monovalent degraders for tunable SMARCA 2/4 degradation
Valentina A Spiteri, Dmitri Segal, Alejandro Correa-Sáez, et al.
The Biochemical Journal
|
November 19, 2015
Biophysical characterization of laforin-carbohydrate interaction
David M Dias, Joana Furtado, Emeric Wasielewski, et al.
Page
of 15