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Journal of Medicinal Chemistry|March 2, 2022
Development of Sulfamoylated 4-(1-Phenyl-1H-1,2,3-triazol-4-yl)phenol Derivatives as Potent Steroid Sulfatase Inhibitors for Efficient Treatment of Breast CancerKarol Biernacki, Olga Ciupak, Mateusz Daśko, et al.Cells|October 23, 2021
Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in RatsElena Lucarini, Alessio Nocentini, Alessandro Bonardi, et al.Bioorganic Chemistry|July 13, 2019
Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activityWagdy M Eldehna, Mohamed A Abdelrahman, Alessio Nocentini, et al.European Journal of Medicinal Chemistry|August 13, 2017
Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studiesWagdy M Eldehna, Mahmoud F Abo-Ashour, Alessio Nocentini, et al.European Journal of Medicinal Chemistry|October 20, 2019
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insightsMahmoud F Abo-Ashour, Wagdy M Eldehna, Alessio Nocentini, et al.International Journal of Molecular Sciences|May 30, 2019
Novel Diamide-Based Benzenesulfonamides as Selective Carbonic Anhydrase IX Inhibitors Endowed with Antitumor Activity: Synthesis, Biological Evaluation and In Silico InsightsMohamed A Abdelrahman, Wagdy M Eldehna, Alessio Nocentini, et al.Journal of Medicinal Chemistry|April 29, 2026
Discovery of a Mixed and Prodrug-Like Inhibition Mechanism for Phosphocoumarins and Phosphoquinolinones against Human Carbonic AnhydrasesAlessio Nocentini, Simone Giovannuzzi, Vincenzo Alterio, et al.European Journal of Medicinal Chemistry|February 16, 2023
4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessmentsMahmoud A Ragab, Wagdy M Eldehna, Alessio Nocentini, et al.European Journal of Medicinal Chemistry|November 17, 2018
Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agentsWagdy M Eldehna, Mahmoud F Abo-Ashour, Alessio Nocentini, et al.European Journal of Medicinal Chemistry|April 11, 2018
2-Benzylpiperazine: A new scaffold for potent human carbonic anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agentsNiccolò Chiaramonte, Silvia Bua, Marta Ferraroni, et al.Pageof 29