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Nature Cancer|November 2, 2024
Recapitulating the adenoma-carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoidsTomohiro Mizutani, Matteo Boretto, Sangho Lim, et al.Science Advances|February 26, 2025
Organoid drug profiling identifies methotrexate as a therapy for SCCOHT, a rare pediatric cancerSeok-Young Kim, Tamar A E de Weert, Marijn Vermeulen, et al.Disease Models & Mechanisms|January 16, 2010
Conversion of metaplastic Barrett's epithelium into post-mitotic goblet cells by gamma-secretase inhibitionVivianda Menke, Johan H van Es, Wim de Lau, et al.Nature|December 19, 2008
Crypt stem cells as the cells-of-origin of intestinal cancerNick Barker, Rachel A Ridgway, Johan H van Es, et al.Cell Systems|February 12, 2026
Live-cell single-vRNP imaging identifies viral gene expression signatures that shape influenza infection heterogeneityHuib H Rabouw, Janin Schokolowski, Micha Müller, et al.Nature Neuroscience|June 9, 2016
YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cellsYannick Poitelon, Camila Lopez-Anido, Kathleen Catignas, et al.Life Science Alliance|August 10, 2021
Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoidsMaarten H Geurts, Eyleen de Poel, Cayetano Pleguezuelos-Manzano, et al.Stem Cell Reports|January 4, 2016
Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt SignalsMartti Maimets, Cecilia Rocchi, Reinier Bron, et al.Biofabrication|June 1, 2018
Bioengineered bile ducts recapitulate key cholangiocyte functionsChen Chen, Paulus G M Jochems, Lucia Salz, et al.Molecular and Cellular Biology|March 7, 2012
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewalJohan H van Es, Andrea Haegebarth, Pekka Kujala, et al.Pageof 66