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Nature Genetics|September 1, 2009
p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional miceYvonne Begus-Nahrmann, André Lechel, Anna C Obenauf, et al.
Cell Stem Cell|December 10, 2013
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patientsGerald Schwank, Bon-Kyoung Koo, Valentina Sasselli, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 27, 2021
Single-cell atlas of developing murine adrenal gland reveals relation of Schwann cell precursor signature to neuroblastoma phenotypeEvelyn S Hanemaaijer, Thanasis Margaritis, Karin Sanders, et al.
The Journal of Clinical Investigation|December 20, 2022
Loss of LGR4/GPR48 causes severe neonatal salt wasting due to disrupted WNT signaling altering adrenal zonationCécily Lucas, Kay-Sara Sauter, Michael Steigert, et al.
Cell Stem Cell|March 23, 2011
The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapseAnna Merlos-Suárez, Francisco M Barriga, Peter Jung, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 9, 2017
Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoidsArianna Fumagalli, Jarno Drost, Saskia J E Suijkerbuijk, et al.
Neoplasia (New York, N.Y.)|October 20, 2025
FER kinase governs invasive growth of head and neck squamous cell carcinoma through dynamic control of growth factor receptor activityPeter D Haughton, Lotte N F L Enserink, Sandra Tavares, et al.
Cell|October 5, 2010
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cellsHugo J Snippert, Laurens G van der Flier, Toshiro Sato, et al.
Science (New York, N.Y.)|September 16, 2017
Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancerJarno Drost, Ruben van Boxtel, Francis Blokzijl, et al.
Nature Methods|December 20, 2017
BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistanceAlexandra A Duarte, Ewa Gogola, Norman Sachs, et al.
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