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Biorxiv : the Preprint Server for Biology|May 3, 2023
Dissecting the molecular basis for the modulation of neurotransmitter GPCR signaling by GINIPAlex Luebbers, Myles Zhou, Stephen J Eyles, et al.Biorxiv : the Preprint Server for Biology|September 4, 2024
Direct detection of endogenous Gαi activity in cells with a sensitive conformational biosensorAlex Luebbers, Remi Janicot, Jingyi Zhao, et al.Science Signaling|March 25, 2025
A sensitive biosensor of endogenous Gαi activity enables the accurate characterization of endogenous GPCR agonist responsesAlex Luebbers, Remi Janicot, Jingyi Zhao, et al.Science Signaling|February 6, 2020
Probing the mutational landscape of regulators of G protein signaling proteins in cancerVincent DiGiacomo, Marcin Maziarz, Alex Luebbers, et al.Elife|September 16, 2020
Optogenetic activation of heterotrimeric G-proteins by LOV2GIVe, a rationally engineered modular proteinMikel Garcia-Marcos, Kshitij Parag-Sharma, Arthur Marivin, et al.Structure (London, England : 1993)|November 21, 2023
Dissecting the molecular basis for the modulation of neurotransmitter GPCR signaling by GINIPAlex Luebbers, Alberto J Gonzalez-Hernandez, Myles Zhou, et al.The Journal of Biological Chemistry|October 25, 2018
Atypical activation of the G protein Gαq by the oncogenic mutation Q209PMarcin Maziarz, Anthony Leyme, Arthur Marivin, et al.The Journal of Biological Chemistry|September 9, 2018
A biochemical and genetic discovery pipeline identifies PLCδ4b as a nonreceptor activator of heterotrimeric G-proteinsMarcin Maziarz, Stefan Broselid, Vincent DiGiacomo, et al.Molecular Cell|June 30, 2023
Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different G protein subunitsJong-Chan Park, Alex Luebbers, Maria Dao, et al.Biorxiv : the Preprint Server for Biology|January 23, 2024
Direct interrogation of context-dependent GPCR activity with a universal biosensor platformRemi Janicot, Marcin Maziarz, Jong-Chan Park, et al.Pageof 2