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ACS Chemical Biology
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May 9, 2015
Synthetic Proteins Potently and Selectively Bind the Oncoprotein Gankyrin, Modulate Its Interaction with S6 ATPase, and Suppress Gankyrin/MDM2-Dependent Ubiquitination of p53
Alex M Chapman, Brian R McNaughton
Cell Chemical Biology
|
May 21, 2016
Scratching the Surface: Resurfacing Proteins to Endow New Properties and Function
Alex M Chapman, Brian R McNaughton
ACS Chemical Biology
|
August 20, 2014
Resurfaced shape complementary proteins that selectively bind the oncoprotein gankyrin
Alex M Chapman, Brian R McNaughton
Molecular Biosystems
|
June 14, 2012
Split-superpositive GFP reassembly is a fast, efficient, and robust method for detecting protein-protein interactions in vivo
Brett D Blakeley, Alex M Chapman, Brian R McNaughton
Biochemistry
|
October 25, 2014
Characterization of the binding interaction between the oncoprotein gankyrin and a grafted S6 ATPase
Alex M Chapman, Bryce E Rogers, Brian R McNaughton
Chembiochem : a European Journal of Chemical Biology
|
December 6, 2014
GLUE that sticks to HIV: a helix-grafted GLUE protein that selectively binds the HIV gp41 N-terminal helical region
Susanne N Walker, Rachel L Tennyson, Alex M Chapman, et al.
The Journal of Biological Chemistry
|
May 4, 2024
4S-fluorination of ProB29 in insulin lispro slows fibril formation
Stephanie L Breunig, Alex M Chapman, Jeanne LeBon, et al.
Journal of Medicinal Chemistry
|
March 6, 2023
Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis <i>In Vivo</i>
John T Randolph, Matthew J O'Connor, Fei Han, et al.
Journal of Medicinal Chemistry
|
June 5, 2025
Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen
Yunsong Tong, Kenton A Baker, Alex M Chapman, et al.
Journal of Medicinal Chemistry
|
May 25, 2026
Discovery of Potent and Orally Bioavailable Novel Cluster of Differentiation 38 (CD38) Small Molecule Inhibitors
Reza Shiroodi, Timothy J Montavon, Brandon M Nelson, et al.
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of 1
Search research articles
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Showing results (1-10 of 10) with videos related to
Sort By:
Page
of 1
ACS Chemical Biology
|
May 9, 2015
Synthetic Proteins Potently and Selectively Bind the Oncoprotein Gankyrin, Modulate Its Interaction with S6 ATPase, and Suppress Gankyrin/MDM2-Dependent Ubiquitination of p53
Alex M Chapman, Brian R McNaughton
Cell Chemical Biology
|
May 21, 2016
Scratching the Surface: Resurfacing Proteins to Endow New Properties and Function
Alex M Chapman, Brian R McNaughton
ACS Chemical Biology
|
August 20, 2014
Resurfaced shape complementary proteins that selectively bind the oncoprotein gankyrin
Alex M Chapman, Brian R McNaughton
Molecular Biosystems
|
June 14, 2012
Split-superpositive GFP reassembly is a fast, efficient, and robust method for detecting protein-protein interactions in vivo
Brett D Blakeley, Alex M Chapman, Brian R McNaughton
Biochemistry
|
October 25, 2014
Characterization of the binding interaction between the oncoprotein gankyrin and a grafted S6 ATPase
Alex M Chapman, Bryce E Rogers, Brian R McNaughton
Chembiochem : a European Journal of Chemical Biology
|
December 6, 2014
GLUE that sticks to HIV: a helix-grafted GLUE protein that selectively binds the HIV gp41 N-terminal helical region
Susanne N Walker, Rachel L Tennyson, Alex M Chapman, et al.
The Journal of Biological Chemistry
|
May 4, 2024
4S-fluorination of ProB29 in insulin lispro slows fibril formation
Stephanie L Breunig, Alex M Chapman, Jeanne LeBon, et al.
Journal of Medicinal Chemistry
|
March 6, 2023
Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis <i>In Vivo</i>
John T Randolph, Matthew J O'Connor, Fei Han, et al.
Journal of Medicinal Chemistry
|
June 5, 2025
Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen
Yunsong Tong, Kenton A Baker, Alex M Chapman, et al.
Journal of Medicinal Chemistry
|
May 25, 2026
Discovery of Potent and Orally Bioavailable Novel Cluster of Differentiation 38 (CD38) Small Molecule Inhibitors
Reza Shiroodi, Timothy J Montavon, Brandon M Nelson, et al.
Page
of 1