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Biorxiv : the Preprint Server for Biology|January 16, 2026
Within-host adaptive evolution is limited by genetic drift in experimental human influenza A virus infectionsLucas M Ferreri, Nahara Vargas-Maldonado, Valerie Le Sage, et al.Influenza and Other Respiratory Viruses|May 21, 2009
A plant-produced influenza subunit vaccine protects ferrets against virus challengeVadim Mett, Konstantin Musiychuk, Hong Bi, et al.The New England Journal of Medicine|June 22, 2022
Vaccine Efficacy in Adults in a Respiratory Syncytial Virus Challenge StudyBeate Schmoele-Thoma, Agnieszka M Zareba, Qin Jiang, et al.Biologicals : Journal of the International Association of Biological Standardization|October 8, 2021
Controlled Human Infection Studies: Proposals for guidance on how to design, develop and produce a challenge strainIsabelle Bekeredjian-Ding, Jean-Hugues Trouvin, Hilde Depraetere, et al.Science Immunology|February 9, 2024
Mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge in seronegative adultsHelen R Wagstaffe, Ryan S Thwaites, Arnold Reynaldi, et al.Nature Communications|December 7, 2025
Pre-existing and early cellular immune factors correlate with functionally complete protection against primary controlled human SARS-CoV-2 infectionHelen R Wagstaffe, Ryan S Thwaites, Jasmin K Sidhu, et al.Medrxiv : the Preprint Server for Health Sciences|November 24, 2025
Controlled human influenza infection reveals heterogeneous expulsion of infectious virus into airNahara Vargas-Maldonado, Nishit Shetty, Lucas M Ferreri, et al.Nature|June 19, 2024
Human SARS-CoV-2 challenge uncovers local and systemic response dynamicsRik G H Lindeboom, Kaylee B Worlock, Lisa M Dratva, et al.Pageof 3