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ACS Earth & Space Chemistry|August 27, 2025
Laboratory Measurements of Ferric Chloride (FeCl<sub>3</sub>) under Venusian ConditionsJoanna V Egan, Alexander D James, John M C PlaneJournal of the American Chemical Society|May 23, 2022
Insights into the Chemistry of Iodine New Particle Formation: The Role of Iodine Oxides and the Source of Iodic AcidJuan Carlos Gómez Martín, Thomas R Lewis, Alexander D James, et al.Pharmacology Research & Perspectives|June 12, 2020
An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME dataAlexander D James, Hilmar Schiller, Cyrille Marvalin, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 9, 2018
Metabolism and Disposition of Siponimod, a Novel Selective S1P<sub>1</sub>/S1P<sub>5</sub> Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative MetabolismUlrike Glaenzel, Yi Jin, Robert Nufer, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 6, 2025
Cross-industry demonstration of the validity of the mixed matrix method for the assessment of cross-species exposure coverage of human circulating drug metabolitesAlexander D James, Christian Lanshoeft, Gregory S Steeno, et al.Clinical Pharmacology and Therapeutics|November 29, 2023
Non-Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion PieceGraeme C Young, Douglas K Spracklin, Alexander D James, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 12, 2024
Recommendations on the Use of Multiple Labels in Human Mass Balance StudiesFilip Cuyckens, Mette G Hvenegaard, Kenneth C Cassidy, et al.Clinical Pharmacology and Therapeutics|June 23, 2022
Considerations for Human ADME Strategy and Design Paradigm Shift(s) - An Industry White PaperGraeme C Young, Douglas K Spracklin, Alexander D James, et al.Clinical Pharmacology and Therapeutics|December 17, 2025
Guided Sample Pooling in Human Mass Balance Studies: A Recommended Strategic Decision FrameworkFilip Cuyckens, Wenying Li, Adam M Auclair, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 1, 2018
A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the "Metabolites in Safety Testing" Regulatory GuidanceSimone Schadt, Bojan Bister, Swapan K Chowdhury, et al.Pageof 2