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ACS Medicinal Chemistry Letters|January 14, 2026
Discovery and Characterization of Diverse Non-nucleotide Inhibitors of DNPH1 Using an Integrated Hit Finding StrategyBenjamin C Whitehurst, Niall A Anderson, Argyrides Argyrou, et al.
Cell Reports|July 21, 2012
The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2βRafael E Luna, Haribabu Arthanari, Hiroyuki Hiraishi, et al.
ACS Medicinal Chemistry Letters|July 17, 2024
Fragment-Based Discovery of Novel MUS81 InhibitorsGavin W Collie, Ulf Börjesson, Yunhua Chen, et al.
Journal of Medicinal Chemistry|June 25, 2024
Design of a Lead-Like Cysteine-Targeting Covalent Library and the Identification of Hits to Cys55 of Bfl-1Simon C C Lucas, Alexander G Milbradt, J Henry Blackwell, et al.
Journal of Medicinal Chemistry|November 6, 2025
Discovery and Optimization of a Non-Nucleoside-Based Series of Inhibitors of 2'-Deoxynucleoside 5'-Monophosphate Glycosidase (DNPH1)Bernard Barlaam, Luz Alonso-Crisostomo, Niall A Anderson, et al.
Journal of Medicinal Chemistry|September 18, 2024
Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 InhibitorsSimon C C Lucas, J Henry Blackwell, Ulf Börjesson, et al.
ACS Medicinal Chemistry Letters|August 20, 2025
Discovery of Small-Molecule Ligands for the E3 Ligase STUB1/CHIP from a DNA-Encoded Library ScreenSimon C C Lucas, Alexander G Milbradt, Jason Breed, et al.
Journal of Medicinal Chemistry|November 3, 2025
Use of Direct-to-Biology Strategies for the Discovery of 2'-Deoxynucleoside 5'-Monophosphate N-Glycosidase (DNPH1) PROTACsNiall A Anderson, Bernard Barlaam, Argyrides Argyrou, et al.
Journal of Medicinal Chemistry|December 23, 2025
Optimization and Chemoproteomic Profiling of a Selective, Covalent Bfl-1-Targeting Cellular ToolJ Henry Blackwell, Simon C C Lucas, Giovanni Battocchio, et al.
ACS Medicinal Chemistry Letters|June 19, 2024
Identification and Evaluation of Reversible Covalent Binders to Cys55 of Bfl-1 from a DNA-Encoded Chemical Library ScreenSimon C C Lucas, J Henry Blackwell, Ulf Börjesson, et al.
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