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Alexander J Smith

Showing results (101-110 of 113) with videos related to

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Human Gene Therapy|March 28, 2018
Assessment of AAV Vector Tropisms for Mouse and Human Pluripotent Stem Cell-Derived RPE and Photoreceptor CellsAnai Gonzalez-Cordero, Debbie Goh, Kamil Kruczek, et al.
The New England Journal of Medicine|April 29, 2008
Effect of gene therapy on visual function in Leber's congenital amaurosisJames W B Bainbridge, Alexander J Smith, Susie S Barker, et al.
Plos One|March 14, 2012
Leber congenital amaurosis associated with AIPL1: challenges in ascribing disease causation, clinical findings, and implications for gene therapyMei Hong Tan, Donna S Mackay, Jill Cowing, et al.
Human Gene Therapy|December 29, 2025
Brain-Directed AAV Gene Therapy Rescues a Mouse Model of the CLN5 Form of Neuronal Ceroid Lipofuscinosis Disease and Normalizes a Blood Plasma Biomarker of NeurodegenerationWenfei Liu, Amy F Geard, Giulia Massaro, et al.
Cell Reports|April 21, 2021
Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptorsJoana Ribeiro, Christopher A Procyk, Emma L West, et al.
Stem Cells (Dayton, Ohio)|May 4, 2026
Transplantation of human stem cell-derived cone photoreceptors partially restores vision in aged rd1 mice with advanced retinal degenerationChristopher A Procyk, Anna Melati, Menahil Tariq, et al.
Ophthalmology|June 10, 2018
Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in Macular DegenerationManjit S Mehat, Venki Sundaram, Caterina Ripamonti, et al.
Stem Cell Reports|August 29, 2017
Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone PhotoreceptorsAnai Gonzalez-Cordero, Kamil Kruczek, Arifa Naeem, et al.
American Journal of Ophthalmology|May 12, 2023
First-in-Human Gene Therapy Trial of AAV8-hCARp.hCNGB3 in Adults and Children With CNGB3-associated AchromatopsiaMichel Michaelides, Nashila Hirji, Sui Chien Wong, et al.
Lancet (London, England)|February 22, 2025
Gene therapy in children with AIPL1-associated severe retinal dystrophy: an open-label, first-in-human interventional studyMichel Michaelides, Yannik Laich, Sui Chien Wong, et al.
Pageof 12

Showing results (101-110 of 113) with videos related to

Sort By:
Pageof 12
Human Gene Therapy|March 28, 2018
Assessment of AAV Vector Tropisms for Mouse and Human Pluripotent Stem Cell-Derived RPE and Photoreceptor CellsAnai Gonzalez-Cordero, Debbie Goh, Kamil Kruczek, et al.
The New England Journal of Medicine|April 29, 2008
Effect of gene therapy on visual function in Leber's congenital amaurosisJames W B Bainbridge, Alexander J Smith, Susie S Barker, et al.
Plos One|March 14, 2012
Leber congenital amaurosis associated with AIPL1: challenges in ascribing disease causation, clinical findings, and implications for gene therapyMei Hong Tan, Donna S Mackay, Jill Cowing, et al.
Human Gene Therapy|December 29, 2025
Brain-Directed AAV Gene Therapy Rescues a Mouse Model of the CLN5 Form of Neuronal Ceroid Lipofuscinosis Disease and Normalizes a Blood Plasma Biomarker of NeurodegenerationWenfei Liu, Amy F Geard, Giulia Massaro, et al.
Cell Reports|April 21, 2021
Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptorsJoana Ribeiro, Christopher A Procyk, Emma L West, et al.
Stem Cells (Dayton, Ohio)|May 4, 2026
Transplantation of human stem cell-derived cone photoreceptors partially restores vision in aged rd1 mice with advanced retinal degenerationChristopher A Procyk, Anna Melati, Menahil Tariq, et al.
Ophthalmology|June 10, 2018
Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in Macular DegenerationManjit S Mehat, Venki Sundaram, Caterina Ripamonti, et al.
Stem Cell Reports|August 29, 2017
Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone PhotoreceptorsAnai Gonzalez-Cordero, Kamil Kruczek, Arifa Naeem, et al.
American Journal of Ophthalmology|May 12, 2023
First-in-Human Gene Therapy Trial of AAV8-hCARp.hCNGB3 in Adults and Children With CNGB3-associated AchromatopsiaMichel Michaelides, Nashila Hirji, Sui Chien Wong, et al.
Lancet (London, England)|February 22, 2025
Gene therapy in children with AIPL1-associated severe retinal dystrophy: an open-label, first-in-human interventional studyMichel Michaelides, Yannik Laich, Sui Chien Wong, et al.
Pageof 12