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Science Translational Medicine|October 13, 2021
Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomasStefan R Sweha, Chan Chung, Siva Kumar Natarajan, et al.Nature Communications|February 6, 2019
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovaryYibo Xue, Brian Meehan, Elizabeth Macdonald, et al.Acta Neuropathologica|July 23, 2017
Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcomePooja Panwalkar, Jonathan Clark, Vijay Ramaswamy, et al.Nature|February 4, 2026
ZFTA-RELA ependymomas make itaconate to epigenetically drive fusion expressionSiva Kumar Natarajan, Joanna Lum, James Haggerty Skeans, et al.Science Translational Medicine|October 6, 2021
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomasPooja Panwalkar, Benita Tamrazi, Derek Dang, et al.Cancer Cell|May 16, 2025
Isocitrate dehydrogenase 1 primes group-3 medulloblastomas for cuproptosisDerek Dang, Akash Deogharkar, John McKolay, et al.Science (New York, N.Y.)|December 18, 2010
The genetic landscape of the childhood cancer medulloblastomaD Williams Parsons, Meng Li, Xiaosong Zhang, et al.The Lancet. Oncology|April 18, 2015
Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysisJonathon Torchia, Daniel Picard, Lucie Lafay-Cousin, et al.Cancer Discovery|August 16, 2023
Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic PathwaysSriram Venneti, Abed Rahman Kawakibi, Sunjong Ji, et al.Cancer Cell|December 14, 2016
Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid TumorsJonathon Torchia, Brian Golbourn, Shengrui Feng, et al.Pageof 9