Showing results (1-10 of 12) with videos related to
Sort By:
Pageof 2
Biochemistry|November 5, 2008
2.3 A X-ray structure of the heme-bound GAF domain of sensory histidine kinase DosT of Mycobacterium tuberculosisLarissa M Podust, Alexandra Ioanoviciu, Paul R Ortiz de MontellanoJournal of Medicinal Chemistry|July 22, 2005
Synthesis and mechanism of action studies of a series of norindenoisoquinoline topoisomerase I poisons reveal an inhibitor with a flipped orientation in the ternary DNA-enzyme-inhibitor complex as determined by X-ray crystallographic analysisAlexandra Ioanoviciu, Smitha Antony, Yves Pommier, et al.Biochemistry|August 7, 2007
Interdomain interactions within the two-component heme-based sensor DevS from Mycobacterium tuberculosisErik T Yukl, Alexandra Ioanoviciu, Paul R Ortiz de Montellano, et al.Biochemistry|March 21, 2007
DevS, a heme-containing two-component oxygen sensor of Mycobacterium tuberculosisAlexandra Ioanoviciu, Erik T Yukl, Pierre Moënne-Loccoz, et al.Biochemistry|May 26, 2009
DevS oxy complex stability identifies this heme protein as a gas sensor in Mycobacterium tuberculosis dormancyAlexandra Ioanoviciu, Yergalem T Meharenna, Thomas L Poulos, et al.Biochemistry|November 4, 2008
A distal tyrosine residue is required for ligand discrimination in DevS from Mycobacterium tuberculosisErik T Yukl, Alexandra Ioanoviciu, Michiko M Nakano, et al.Nature Neuroscience|July 21, 2015
Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic miceMeaghan Morris, Giselle M Knudsen, Sumihiro Maeda, et al.Biochemistry|January 22, 2011
Nitric oxide dioxygenation reaction in DevS and the initial response to nitric oxide in Mycobacterium tuberculosisErik T Yukl, Alexandra Ioanoviciu, Santhosh Sivaramakrishnan, et al.Journal of Medicinal Chemistry|October 13, 2006
Synthesis and evaluation of indenoisoquinoline topoisomerase I inhibitors substituted with nitrogen heterocyclesMuthukaman Nagarajan, Andrew Morrell, Alexandra Ioanoviciu, et al.Molecular Cancer Therapeutics|March 1, 2006
A novel norindenoisoquinoline structure reveals a common interfacial inhibitor paradigm for ternary trapping of the topoisomerase I-DNA covalent complexChristophe Marchand, Smitha Antony, Kurt W Kohn, et al.Pageof 2