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Blood|April 29, 2020
CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemiaJohannes Schmoellerl, Inês Amorim Monteiro Barbosa, Thomas Eder, et al.
Biorxiv : the Preprint Server for Biology|January 30, 2023
MCB-613 exploits a collateral sensitivity in drug resistant EGFR-mutant non-small cell lung cancer through covalent inhibition of KEAP1Christopher F Bassil, Gray R Anderson, Benjamin Mayro, et al.
Nature Communications|July 7, 2025
JAK2 inhibition mediates clonal selection of RAS pathway mutations in myeloproliferative neoplasmsNabih Maslah, Nina Kaci, Blandine Roux, et al.
The Journal of Experimental Medicine|July 27, 2016
BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic miceMohamed-Amine Hamouda, Arnaud Jacquel, Guillaume Robert, et al.
Science Translational Medicine|March 9, 2018
Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemiaFlorence F Wagner, Lina Benajiba, Arthur J Campbell, et al.
Cancer Cell|June 18, 2013
In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signalingPeter G Miller, Fatima Al-Shahrour, Kimberly A Hartwell, et al.
Nature Cancer|June 6, 2022
P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemiaKevin H Lin, Justine C Rutter, Abigail Xie, et al.
Cancer Discovery|August 23, 2020
The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting TherapiesAngela Su, Frank Ling, Camille Vaganay, et al.
Nature Communications|January 14, 2026
EGFR inhibitor-resistant lung cancers exhibit collateral sensitivity to a covalent, cysteine-independent KEAP1 oligomerizing molecular bridgeChristopher F Bassil, Kerry Dillon, Gray R Anderson, et al.
Leukemia|April 27, 2022
Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemiaBryann Pardieu, Justine Pasanisi, Frank Ling, et al.
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