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European Journal of Medicinal Chemistry|August 26, 2016
Substituted 4-morpholine N-arylsulfonamides as γ-secretase inhibitorsZhiqiang Zhao, Dmitri A Pissarnitski, Hubert B Josien, et al.Bioorganic & Medicinal Chemistry Letters|October 24, 2017
Concise syntheses and HCV NS5B polymerase inhibition of (2'R)-3 and (2'S)-2'-ethynyluridine-10 and related nucleosidesFrank Bennett, Alexei V Buevich, Hsueh-Cheng Huang, et al.ACS Medicinal Chemistry Letters|October 16, 2024
Rapid Affinity and Microsomal Stability Ranking of Crude Mixture Libraries of Histone Deacetylase InhibitorsSriram Tyagarajan, Christine L Andrews, Douglas C Beshore, et al.The Journal of Organic Chemistry|December 10, 2016
Characterization and Synthesis of Eudistidine C, a Bioactive Marine Alkaloid with an Intriguing Molecular ScaffoldSusanna T S Chan, Roger R Nani, Evan A Schauer, et al.Nature Communications|January 3, 2026
WRN structural flexibility showcased through fragment-based lead discovery of inhibitorsRachel L Palte, Mihir Mandal, Justyna Sikorska, et al.Journal of Medicinal Chemistry|March 29, 2022
Lead Optimization to Advance Protease-Activated Receptor-1 Antagonists in Early DiscoveryMihirbaran Mandal, Maria Madeira, Rupesh P Amin, et al.Journal of Medicinal Chemistry|March 22, 2017
Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO InhibitorMihirbaran Mandal, Zheng Tan, Christina Madsen-Duggan, et al.Journal of Medicinal Chemistry|December 8, 2022
Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical CandidatesMihirbaran Mandal, Li Xiao, Weidong Pan, et al.Science (New York, N.Y.)|August 22, 2020
An orally available non-nucleotide STING agonist with antitumor activityBo-Sheng Pan, Samanthi A Perera, Jennifer A Piesvaux, et al.ACS Medicinal Chemistry Letters|July 14, 2026
Discovery of MK-2118, a Small-Molecule Agonist of STINGTimothy Henderson, Michael D Altman, Alexei V Buevich, et al.Pageof 6