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Protein Science : a Publication of the Protein Society
|
September 12, 2014
Structures of a pan-specific antagonist antibody complexed to different isoforms of TGFβ reveal structural plasticity of antibody-antigen interactions
Aaron Moulin, Magali Mathieu, Catherine Lawrence, et al.
Journal of Medicinal Chemistry
|
June 30, 2016
Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844)
Antonio Ugolini, Mireille Kenigsberg, Alexey Rak, et al.
Molecular Cancer Therapeutics
|
January 8, 2026
TPP-45142-an Anti-HER2 T cell Engager-Designed for Selective HER2-Low Cancer Immunotherapy
Evelyn De Tavernier, Peter S Kim, Eduardo M Bruch, et al.
The Journal of Biological Chemistry
|
November 14, 2014
Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule
Gejing Deng, Junqing Shen, Ming Yin, et al.
Nucleic Acids Research
|
October 23, 2023
Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction
Antonia Kefala Stavridi, Amandine Gontier, Vincent Morin, et al.
Scientific Reports
|
January 7, 2015
Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents
Guy Griebel, Philippe Pichat, Sandra Beeské, et al.
Journal of Medicinal Chemistry
|
April 25, 2012
Discovery and optimization of new benzimidazole- and benzoxazole-pyrimidone selective PI3Kβ inhibitors for the treatment of phosphatase and TENsin homologue (PTEN)-deficient cancers
Victor Certal, Frank Halley, Angela Virone-Oddos, et al.
Blood
|
June 10, 2025
Biallelic antigen escape is a mechanism of resistance to anti-CD38 antibodies in multiple myeloma
Benjamin T Diamond, Linda B Baughn, Mansour Poorebrahim, et al.
Cell
|
February 24, 2023
Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents
Jidong Zhang, Christine Lair, Christine Roubert, et al.
Journal of Medicinal Chemistry
|
November 14, 2019
Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3<i>S</i>)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7<i>H</i>-benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer
Youssef El-Ahmad, Michel Tabart, Frank Halley, et al.
Page
of 6
Search research articles
Search
Showing results (41-50 of 51) with videos related to
Sort By:
Page
of 6
Protein Science : a Publication of the Protein Society
|
September 12, 2014
Structures of a pan-specific antagonist antibody complexed to different isoforms of TGFβ reveal structural plasticity of antibody-antigen interactions
Aaron Moulin, Magali Mathieu, Catherine Lawrence, et al.
Journal of Medicinal Chemistry
|
June 30, 2016
Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844)
Antonio Ugolini, Mireille Kenigsberg, Alexey Rak, et al.
Molecular Cancer Therapeutics
|
January 8, 2026
TPP-45142-an Anti-HER2 T cell Engager-Designed for Selective HER2-Low Cancer Immunotherapy
Evelyn De Tavernier, Peter S Kim, Eduardo M Bruch, et al.
The Journal of Biological Chemistry
|
November 14, 2014
Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule
Gejing Deng, Junqing Shen, Ming Yin, et al.
Nucleic Acids Research
|
October 23, 2023
Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction
Antonia Kefala Stavridi, Amandine Gontier, Vincent Morin, et al.
Scientific Reports
|
January 7, 2015
Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents
Guy Griebel, Philippe Pichat, Sandra Beeské, et al.
Journal of Medicinal Chemistry
|
April 25, 2012
Discovery and optimization of new benzimidazole- and benzoxazole-pyrimidone selective PI3Kβ inhibitors for the treatment of phosphatase and TENsin homologue (PTEN)-deficient cancers
Victor Certal, Frank Halley, Angela Virone-Oddos, et al.
Blood
|
June 10, 2025
Biallelic antigen escape is a mechanism of resistance to anti-CD38 antibodies in multiple myeloma
Benjamin T Diamond, Linda B Baughn, Mansour Poorebrahim, et al.
Cell
|
February 24, 2023
Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents
Jidong Zhang, Christine Lair, Christine Roubert, et al.
Journal of Medicinal Chemistry
|
November 14, 2019
Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3<i>S</i>)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7<i>H</i>-benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer
Youssef El-Ahmad, Michel Tabart, Frank Halley, et al.
Page
of 6