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Nature Communications|September 6, 2022
Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degenerationStefan Gerhardy, Mark Ultsch, Wanjian Tang, et al.Journal of Molecular Biology|September 24, 2011
Tilt-pair analysis of images from a range of different specimens in single-particle electron cryomicroscopyRichard Henderson, Shaoxia Chen, James Z Chen, et al.Nature Communications|July 13, 2019
Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activationMichael J Holliday, Axel Witt, Alejandro Rodríguez Gama, et al.Nature Communications|April 9, 2026
Complete inhibition of β-tryptase by tetramer dissociation and active site allostery due to a single antibody residueHenry R Maun, Caleigh M Azumaya, Benjamin T Walters, et al.Nature Microbiology|December 10, 2025
Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growthAntonio Serrano, Charles Puerner, Louis Chevalier, et al.Nature Communications|September 30, 2025
Disulfide-constrained Fabs overcome target size limitation for high-resolution single particle cryoEMJennifer E Kung, Matthew C Johnson, Dimitry Tegunov, et al.Cell|January 22, 2019
Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider ToxinHui Xu, Tianbo Li, Alexis Rohou, et al.Science (New York, N.Y.)|February 22, 2020
Structure of CD20 in complex with the therapeutic monoclonal antibody rituximabLionel Rougé, Nancy Chiang, Micah Steffek, et al.Nature|October 30, 2024
Autoinhibition of dimeric NINJ1 prevents plasma membrane ruptureSergei Pourmal, Melissa E Truong, Matthew C Johnson, et al.Bioconjugate Chemistry|April 9, 2024
Adapting Ferritin, a Naturally Occurring Protein Cage, to Modulate Intrinsic Agonism of OX40Whitney Shatz-Binder, Caleigh M Azumaya, Brandon Leonard, et al.Pageof 14