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Biochemistry|March 30, 2005
A nucleotide binding site in caspase-9 regulates apoptosome activationDavid Chereau, Hua Zou, Alfred P Spada, et al.Biochemistry|April 12, 2003
Structural and functional analysis of caspase active sitesDavid Chéreau, Lalitha Kodandapani, Kevin J Tomaselli, et al.Toxicological Sciences : an Official Journal of the Society of Toxicology|December 12, 2017
Caspase Inhibition Reduces Hepatic Tissue Factor-Driven Coagulation In Vitro and In VivoAnna K Kopec, Alfred P Spada, Patricia C Contreras, et al.Journal of Molecular Recognition : JMR|July 2, 2003
Conformational restrictions in the active site of unliganded human caspase-3Chao-Zhou Ni, Chenglong Li, Joe C Wu, et al.Journal of Medicinal Chemistry|February 21, 2003
Molecular structures of human factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocketSébastien Maignan, Jean-Pierre Guilloteau, Yong Mi Choi-Sledeski, et al.Bioorganic & Medicinal Chemistry Letters|April 18, 2002
Benzimidazoles and isosteric compounds as potent and selective factor Xa inhibitorsWei He, Barbara Hanney, Michael R Myers, et al.Bioorganic & Medicinal Chemistry Letters|August 28, 2003
Potent quinoxaline-based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: the synthesis and biological activities of RPR127963 an orally bioavailable inhibitorWei He, Michael R Myers, Barbara Hanney, et al.Bioorganic & Medicinal Chemistry Letters|August 28, 2003
Potent quinoxaline-based inhibitors of PDGF receptor tyrosine kinase activity. Part 1: SAR exploration and effective bioisosteric replacement of a phenyl substituentMichael R Myers, Wei He, Barbara Hanney, et al.Bioorganic & Medicinal Chemistry Letters|June 1, 2002
Optimization of the beta-aminoester class of factor Xa inhibitors. Part 1: P(4) and side-chain modifications for improved in vitro potencyMark Czekaj, Scott I Klein, Kevin R Guertin, et al.Hepatology (Baltimore, Md.)|August 1, 2018
Emricasan (IDN-6556) Lowers Portal Pressure in Patients With Compensated Cirrhosis and Severe Portal HypertensionGuadalupe Garcia-Tsao, Michael Fuchs, Mitchell Shiffman, et al.Pageof 2