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Scientific Data|October 21, 2024
A compound-target pairs dataset: differences between drugs, clinical candidates and other bioactive compoundsA Lina Heinzke, Barbara Zdrazil, Paul D Leeson, et al.Nature Chemical Biology|September 20, 2006
Therapeutic intervention based on protein prenylation and associated modificationsMichael H Gelb, Lucas Brunsveld, Christine A Hrycyna, et al.Chembiochem : a European Journal of Chemical Biology|December 14, 2005
Influence of serine O-glycosylation or O-phosphorylation close to the vJun nuclear localisation sequence on nuclear importStefanie Schlummer, Robin Vetter, Norman Kuder, et al.Journal of Medicinal Chemistry|July 1, 2024
Occurrence of "Natural Selection" in Successful Small Molecule Drug DiscoveryA Lina Heinzke, Axel Pahl, Barbara Zdrazil, et al.Chemistry, an Asian Journal|August 10, 2007
Identification of inhibitors for mycobacterial protein tyrosine phosphatase B (MptpB) by biology-oriented synthesis (BIOS)Ivan R Corrêa, Andrea Nören-Müller, Horst-Dieter Ambrosi, et al.Angewandte Chemie (International Ed. in English)|March 5, 2015
Biology-oriented synthesis of a withanolide-inspired compound collection reveals novel modulators of hedgehog signalingJakub Švenda, Michael Sheremet, Lea Kremer, et al.Bioorganic & Medicinal Chemistry|May 22, 2003
Identification of mono- and bisubstrate inhibitors of protein farnesyltransferase and inducers of apoptosis from a pepticinnamin E libraryMichael Thutewohl, Lars Kissau, Boriana Popkirova, et al.JACS Au|December 5, 2022
The Time and Place for Nature in Drug DiscoveryRobert J Young, Sabine L Flitsch, Michael Grigalunas, et al.Science (New York, N.Y.)|October 25, 2003
Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPaseAlexey Rak, Olena Pylypenko, Thomas Durek, et al.Proceedings of the National Academy of Sciences of the United States of America|November 19, 2004
Compound library development guided by protein structure similarity clustering and natural product structureMarcus A Koch, Lars-Oliver Wittenberg, Sudipta Basu, et al.Pageof 49