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Proceedings of the National Academy of Sciences of the United States of America|May 10, 2012
Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasisJoanna D Stewart, Rosemarie Marchan, Michaela S Lesjak, et al.Nature Chemical Biology|June 22, 2019
The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesisLuca Laraia, Alexandra Friese, Dale P Corkery, et al.Journal of Medicinal Chemistry|January 7, 2026
Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras SignalingRuirui Zhang, Maxim A Huetzen, Aylin Binici, et al.Cell Reports|May 7, 2016
Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCsDamir Jacob Illich, Miao Zhang, Andrei Ursu, et al.Nature Cell Biology|May 26, 2009
A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesisGabriele Siegel, Gregor Obernosterer, Roberto Fiore, et al.Angewandte Chemie (International Ed. in English)|December 31, 2024
Phenomics-Based Discovery of Novel Orthosteric Choline Kinase InhibitorsLudwig G Bauer, Jennifer A Ward, Laura Díaz-Sáez, et al.The Journal of Biological Chemistry|March 23, 2017
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channelsHussein N Rubaiy, Melanie J Ludlow, Matthias Henrot, et al.Nature Communications|October 28, 2020
A protein tertiary structure mimetic modulator of the Hippo signalling pathwayHélène Adihou, Ranganath Gopalakrishnan, Tim Förster, et al.Journal of Medicinal Chemistry|December 2, 2022
The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast DifferentiationJana Flegel, Saad Shaaban, Zhi Jun Jia, et al.Proceedings of the National Academy of Sciences of the United States of America|October 5, 2012
A framework for identification of actionable cancer genome dependencies in small cell lung cancerMartin L Sos, Felix Dietlein, Martin Peifer, et al.Pageof 49