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Bioorganic & Medicinal Chemistry Letters|December 3, 2014
Design, synthesis and structure-activity relationships of a novel class of sulfonylpyridine inhibitors of Interleukin-2 inducible T-cell kinase (ITK)Giancarlo Trani, John J Barker, Steven M Bromidge, et al.ACS Medicinal Chemistry Letters|March 19, 2020
Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo ActivityNaomi S Rajapaksa, Alberto Gobbi, Joy Drobnick, et al.Journal of Medicinal Chemistry|May 15, 2019
Development of Potent and Selective Pyrazolopyrimidine IRAK4 InhibitorsMarian C Bryan, Joy Drobnick, Alberto Gobbi, et al.Proceedings of the National Academy of Sciences of the United States of America|September 11, 2013
Polyclonal hyper-IgE mouse model reveals mechanistic insights into antibody class switch recombinationShahram Misaghi, Kate Senger, Tao Sai, et al.Journal of Immunology (Baltimore, Md. : 1950)|June 18, 2014
PILRα negatively regulates mouse inflammatory arthritisYonglian Sun, Patrick Caplazi, Juan Zhang, et al.Science Signaling|December 3, 2015
Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory responseYonglian Sun, Ivan Peng, Joshua D Webster, et al.Science Signaling|April 20, 2017
The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammationKate Senger, Victoria C Pham, Eugene Varfolomeev, et al.Frontiers in Immunology|September 26, 2019
Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and CancerWeiYu Lin, Daqi Xu, Cary D Austin, et al.Science Signaling|June 4, 2020
The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cellsCesar A Corzo, Eugene Varfolomeev, A Francesca Setiadi, et al.Pageof 4