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Neurobiology of Disease|April 11, 2022
Convergence of signalling pathways in innate immune responses and genetic forms of Parkinson's diseaseAdamantios Mamais, Alice Kaganovich, Kirsten HarveyHuman Molecular Genetics|August 22, 2013
Hexokinase activity is required for recruitment of parkin to depolarized mitochondriaMelissa K McCoy, Alice Kaganovich, Iakov N Rudenko, et al.NPJ Parkinson'S Disease|May 1, 2018
Detection of endogenous S1292 LRRK2 autophosphorylation in mouse tissue as a readout for kinase activityJillian H Kluss, Melissa M Conti, Alice Kaganovich, et al.Stem Cell Research|October 9, 2021
Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matchedXylena Reed, Melanie M Cobb, Gaia Skinbinski, et al.Plos One|January 22, 2010
The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylationAzad Kumar, Elisa Greggio, Alexandra Beilina, et al.Journal of Neuroinflammation|October 29, 2018
Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4Isabella Russo, Giulietta Di Benedetto, Alice Kaganovich, et al.Science Translational Medicine|July 27, 2022
Association of a common genetic variant with Parkinson's disease is mediated by microgliaRebekah G Langston, Alexandra Beilina, Xylena Reed, et al.The Biochemical Journal|May 23, 2012
The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutationIakov N Rudenko, Alice Kaganovich, David N Hauser, et al.The Biochemical Journal|March 22, 2017
The G2385R risk factor for Parkinson's disease enhances CHIP-dependent intracellular degradation of LRRK2Iakov N Rudenko, Alice Kaganovich, Rebekah G Langston, et al.Neurobiology of Disease|May 19, 2019
Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrilsIsabella Russo, Alice Kaganovich, Jinhui Ding, et al.Pageof 4