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Biorxiv : the Preprint Server for Biology|February 6, 2026
Inflammatory signaling differentially changes chromatin accessibility and gene expression of the PD- associated kinase LRRK2 between human and miceAlexandra Beilina, Jae-Hyeon Park, Natalie Landeck, et al.
Glia|October 12, 2020
Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytesAlice Filippini, Veronica Mutti, Gaia Faustini, et al.
Neurobiology of Disease|June 6, 2006
Kinase activity is required for the toxic effects of mutant LRRK2/dardarinElisa Greggio, Shushant Jain, Ann Kingsbury, et al.
Cell Reports|May 7, 2020
The Parkinson's Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi NetworkAlexandra Beilina, Luis Bonet-Ponce, Ravindran Kumaran, et al.
Science Translational Medicine|October 15, 2020
LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathiesChangyoun Kim, Alexandria Beilina, Nathan Smith, et al.
Plos Biology|December 16, 2021
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microgliaAdamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, et al.
Plos Biology|May 4, 2022
Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microgliaAdamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 19, 2011
A soluble α-synuclein construct forms a dynamic tetramerWei Wang, Iva Perovic, Johnathan Chittuluru, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 11, 2014
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson diseaseAlexandria Beilina, Iakov N Rudenko, Alice Kaganovich, et al.
Plos One|July 30, 2011
Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissueMichael J Devine, Alice Kaganovich, Mina Ryten, et al.
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