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Nature Chemical Biology|January 6, 2026
Advances in BRET probes for intracellular target engagement studiesJacob L Capener, Martin P Schwalm, James D Vasta, et al.Journal of Medicinal Chemistry|October 24, 2023
Fused Tetrahydroquinolines Are Interfering with Your AssayFrances M Bashore, Joel Annor-Gyamfi, Yuhong Du, et al.European Journal of Medicinal Chemistry|April 18, 2024
Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationshipsChristopher R M Asquith, Michael P East, Tuomo Laitinen, et al.Biorxiv : the Preprint Server for Biology|January 18, 2024
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity RelationshipsChristopher R M Asquith, Michael P East, Tuomo Laitinen, et al.Journal of Medicinal Chemistry|September 16, 2022
Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-CoronavirusesDavid H Drewry, Frances M Potjewyd, Armin Bayati, et al.Alzheimer'S & Dementia (New York, N. Y.)|May 22, 2023
Open drug discovery in Alzheimer's diseaseAlison D Axtman, Paul E Brennan, Tristan Frappier-Brinton, et al.ACS Medicinal Chemistry Letters|April 20, 2023
Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2Zachary W Davis-Gilbert, Andreas Krämer, James E Dunford, et al.Frontiers in Chemical Biology|April 20, 2026
Development of SYK NanoBRET cellular target engagement assays for gain-of-function variantsJacob L Capener, James D Vasta, Vittorio L Katis, et al.Biorxiv : the Preprint Server for Biology|June 25, 2024
Development of SYK NanoBRET Cellular Target Engagement Assays for Gain-of-Function VariantsJacob L Capener, James D Vasta, Vittorio L Katis, et al.Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association|December 26, 2025
Drug DevelopmentKarina Leal, Elizabeth L Zoeller, Gregory A Cary, et al.Pageof 7