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Journal of Neurochemistry|June 30, 2006
Conserved residues in juxtamembrane region of the extracellular domain of nicastrin are essential for gamma-secretase complex formationEmily S Walker, Maribel Martinez, Jun Wang, et al.Science Translational Medicine|December 23, 2011
Mapping the road forward in Alzheimer's diseaseDavid M Holtzman, Alison Goate, Jeffrey Kelly, et al.Alcoholism, Clinical and Experimental Research|June 14, 2018
Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells?Iya Prytkova, Alison Goate, Ronald P Hart, et al.Journal of Neurochemistry|January 25, 2005
Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratiosEmily S Walker, Maribel Martinez, Anne L Brunkan, et al.Neurobiology of Disease|April 2, 2004
Conserved "PAL" sequence in presenilins is essential for gamma-secretase activity, but not required for formation or stabilization of gamma-secretase complexesJun Wang, Anne L Brunkan, Silva Hecimovic, et al.Ebiomedicine|February 6, 2024
Association between pre-dementia psychiatric diagnoses and all-cause dementia is independent from polygenic dementia risks in the UK BiobankYun Freudenberg-Hua, Wentian Li, Un Jung Lee, et al.Journal of Neurochemistry|November 25, 2005
C-terminal PAL motif of presenilin and presenilin homologues required for normal active site conformationJun Wang, Dirk Beher, Andrew C Nyborg, et al.Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition|March 11, 2015
APOE ε4 genotype predicts memory for everyday activitiesHeather R Bailey, Jesse Q Sargent, Shaney Flores, et al.Biochimica Et Biophysica Acta|May 25, 2010
Niemann-Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the beta-secretase pathwayMartina Malnar, Marko Kosicek, Stefan Mitterreiter, et al.Molecular Psychiatry|July 14, 2025
Differential associations of APOE and TREM2 variants with glial fibrillary acidic protein and neurofilament light in plasma of UK Biobank participants support distinct disease mechanismsYun Freudenberg-Hua, Luca Giliberto, Cristina d'Abramo, et al.Pageof 25