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Chemical Research in Toxicology|September 20, 2019
Predicting Drug-Induced Liver Injury with Bayesian Machine LearningDominic P Williams, Stanley E Lazic, Alison J Foster, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|October 3, 2013
A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humansFrida Gustafsson, Alison J Foster, Sunil Sarda, et al.
Archives of Toxicology|March 31, 2015
Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type miceJames A Akingbasote, Alison J Foster, Ian Wilson, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 2, 2012
Characterization of THLE-cytochrome P450 (P450) cell lines: gene expression background and relationship to P450-enzyme activityYalda Soltanpour, Constanze Hilgendorf, Marie M Ahlström, et al.
Toxicology Research|August 10, 2018
Improved hepatic physiology in hepatic cytochrome P450 reductase null (HRN™) mice dosed orally with fenclozic acidJames A Akingbasote, Alison J Foster, Huw B Jones, et al.
Chemical Research in Toxicology|December 14, 2012
Bioactivation of the cannabinoid receptor antagonist rimonabant to a cytotoxic iminium ion metaboliteAlison J Foster, Lucy H Prime, Frida Gustafsson, et al.
Toxicology in Vitro : an International Journal Published in Association with BIBRA|November 6, 2013
Evaluation of the use of imaging parameters for the detection of compound-induced hepatotoxicity in 384-well cultures of HepG2 cells and cryopreserved primary human hepatocytesHelen Garside, Karen F Marcoe, Jessica Chesnut-Speelman, et al.
Biochimica Et Biophysica Acta|May 7, 2013
Glutathione metabolism modeling: a mechanism for liver drug-robustness and a new biomarker strategySuzanne Geenen, Franco B du Preez, Jacky L Snoep, et al.
Toxicology Research|May 27, 2025
Use of new approach methodology for hepatic safety assessment of covalent inhibitor drug candidatesSara Amberntsson, Alison J Foster, Bhavik Chouhan, et al.
The Journal of Pharmacology and Experimental Therapeutics|December 4, 2014
Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonistsJ Gerry Kenna, Simone H Stahl, Julie A Eakins, et al.
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